Results 61 to 70 of about 58,452 (246)
Asymmetric motion of magnetically actuated artificial cilia [PDF]
Lab Chip, 2017,17, 3138-3145, 2018 Most microorganisms use hair-like cilia with asymmetric beating to perform vital bio-physical processes. In this paper, we demonstrate a novel fabrication method for creating magnetic artificial cilia capable of such biologically inspired asymmetrical beating pattern essential for creating microfluidic transport in low Reynolds number.
arxiv +1 more source
The Leishmania major BBSome subunit BBS1 is essential for parasite virulence in the mammalian host [PDF]
, 2013 Bardet–Biedl syndrome (BBS) is a human genetic disorder with a spectrum of symptoms caused by primary cilium dysfunction. The disease is caused by mutations in one of at least 17 identified genes, of which seven encode subunits of the BBSome, a protein ...
Doehl, Johannes +6 more
core +1 more source
Cholesterol in the ciliary membrane as a therapeutic target against cancer
Frontiers in Molecular Biosciences, 2023 Primary cilium is a non-motile, antenna-like structure that develops in the quiescent G0 phase-cell surface. It is composed of an array of axonemal microtubules polymerized from the centrosome/basal body.
Sotai Kimura +7 more
doaj +1 more source
PLoS Genetics, 2023 An essential process during Danio rerio's left-right organizer (Kupffer's Vesicle, KV) formation is the formation of a motile cilium by developing KV cells which extends into the KV lumen. Beating of motile cilia within the KV lumen directs fluid flow to
Abrar A Aljiboury +10 more
doaj +1 more source
The Geometry of Ciliary Dynamics [PDF]
, 2009 Cilia are motile biological appendages that are driven to bend by internal shear stresses between tubulin filaments. A continuum model of ciliary material is constructed that incorporates the essential ciliary constraints: (1) one-dimensional inextensibility of filaments, (2) three-dimensional incompressibility, and (3) shear strain only along ...
arxiv +1 more source
Rab8a and Rab8b are essential for several apical transport pathways but insufficient for ciliogenesis [PDF]
, 2013 The small GTP-binding protein Rab8 is known to play an essential role in intracellular transport and cilia formation. We have previously demonstrated that Rab8a is required for localising apical markers in various organisms.
A. Harada +10 more
core +2 more sources
Ciliary beating patterns map onto a low-dimensional behavioral space that accords with a simple mechanochemical model [PDF]
arXiv, 2021 Biological systems are robust to perturbations at both the genetic and environmental levels. Yet, these same perturbations can elicit variation in behavior. The interplay between functional robustness and behavioral variability is exemplified at the organellar level by the beating of cilia and flagella. The complex bending patterns of cilia emerge from
arxiv
Generic flow profiles induced by a beating cilium [PDF]
Eur. Phys. J. E 35 (2012) 72, 2012 We describe a multipole expansion for the low Reynolds number fluid flows generated by a localized source embedded in a plane with a no-slip boundary condition. It contains 3 independent terms that fall quadratically with the distance and 6 terms that fall with the third power.
arxiv +1 more source
Frontiers in Cellular and Infection Microbiology, 2021 Metorchis orientalis is a neglected zoonotic parasite of the gallbladder and bile duct of poultry, mammals, and humans. It has been widely reported in Asian, including China, Japanese, and Korea, where it is a potential threat to public health.
Jun-Feng Gao +7 more
doaj +1 more source
Realizing the physics of motile cilia synchronization with driven colloids
, 2015 Cilia and flagella in biological systems often show large scale cooperative behaviors such as the synchronization of their beats in "metachronal waves".
Bruot, Nicolas, Cicuta, Pietro
core +1 more source