Results 121 to 130 of about 742,756 (306)

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Hepatic histologic findings in a murine model of diet induced-steatotic liver disease and acute alcohol intake

Annals of Hepatology
Introduction and Objectives: Steatotic liver disease is produced by a range of etiologic agents, among them metabolic and alcoholic. Our aim was to identify the histologic findings produced in the liver after the interaction of steatosis induced by the ...
Gabriela Sarahi Martínez-Mejia, Miriam G. Bautista-Ubaldo, Gabriela Gutiérrez-Reyes, Carolina Guzmán   +3 more
doaj   +1 more source

Identification of hyaluronic acid and chondroitin sulfates in human follicular fluid and their effects on human sperm motility and the outcome of in vitro fertilization [PDF]

, 1996
S. Hamamah, Christiane Wittemer, C. Barthélémy, Colette Richet, Farid Zerimech, Dominique Royère, Pierre Degand   +6 more
openalex   +1 more source

Teaching Python with team‐based learning: using cloud‐based notebooks for interactive coding education

FEBS Open Bio, EarlyView.
This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley   +1 more source

Tracing blastomere fate choices of early embryos in single cell culture [PDF]

, 2010
Blastomeres of early vertebrate embryos undergo numerous fate choices for division, motility, pluripotency maintenance and restriction culminating in various cell lineages.
Chang Ming Li, Haobin Zhao, Jianxin Song, Meisheng Yi, Mingyou Li, Ni Hong, Rong Liu, Ruowen Ge, Yan Yan, Yongming Yuan, Yunhan Hong, Zhendong Li   +11 more
core   +1 more source

Comparing the Motility of Myosin X with Parallel and Anti-Parallel Dimerization Domains [PDF]

, 2016
Matthew A. Caporizzo, Claire E. Fishman, Osamu Satō, Mitsuo Ikebe, Yale E. Goldman   +4 more
openalex   +1 more source

Phosphomimetic mutations near active sites of proteins in Thermus thermophilus suggest a widespread regulatory mechanism

FEBS Open Bio, EarlyView.
In Thermus thermophilus, more than half of the phosphorylation sites identified by proteomic analysis are located near the active site. All phosphomimetic mutants of phosphosites of six enzymes belonging to different families showed severely reduced activity compared with the wild‐type, particularly in the turnover number.
Anzu Nishiwaki, Hiroki Okanishi, Yoshikatsu Kanai, Ryoji Masui   +3 more
wiley   +1 more source

From Pathogenesis to Treatment: Targeting Type-2 Inflammation in Eosinophilic Esophagitis

Biomolecules
Eosinophilic esophagitis (EoE) is a chronic inflammatory disorder of the esophagus. EoE shares a common pathogenetic mechanism with other chronic disorders pertaining to the type 2 inflammatory spectrum, such as atopic dermatitis (AD), allergic rhinitis (
Alberto Barchi, Francesco Vito Mandarino, Mona-Rita Yacoub, Luca Albarello, Luca Massimino, Edoardo Vincenzo Savarino, Federica Ungaro, Sandro Passaretti, Gwen M. C. Masclee, Silvio Danese, Albert J. Bredenoord, Edoardo Vespa   +11 more
doaj   +1 more source

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

FEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado, Leanne Jones, Sonika Divakar, Michael Naidoo, Karen Anthony   +4 more
wiley   +1 more source

Evaluation of oxidative stress according to the pattern of alcohol consumption and in alcoholic liver disease.

Annals of Hepatology
Introduction and Objectives: Alcohol and its metabolites induce damage in the liver, such as: activation of the immune response and oxidative stress.
Adrián Flores-Sánchez, Abigail Hernández-Barragán, Daniela Colector-Sesatti, Andrea Garcia-Avalos, Moisés Martínez-Castillo, Marisela Hernández-Santillan, Jaqueline Córdova-Gallardo, José L. Pérez-Hernandez, Fátima Higuera-De la Tijera, Gabriela Gutiérrez-Reyes   +9 more
doaj   +1 more source