Results 151 to 160 of about 597,542 (311)

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Efficacy and Safety of Glucagon-Like Peptide-1 Receptor Agonists for Obesity Management in Adults With and Without Type 2 Diabetes: A Systematic Review

Journal of Obesity
Jena Velji-Ibrahim, Dhruvil Radadiya, Kalpit Devani, Harsh Patel, Piyush Nathani, Cesare Hassan, Nicola Pugliese, Christopher Thompson, Prateek Sharma   +8 more
doaj   +1 more source

Neuronal responses to cytokines limit intestinal hypermotility and systemic effects of colonic inflammation. [PDF]

iScience
Jung J, Wehmeier A, Xie Z, Horton D, Russler-Germain EV, Schill EM, Miller MJ, Brestoff JR, Newberry R, Kim BS, Hu H, Hsieh CS.   +11 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

CsmR controls both, motility and cell shape, in Haloferax volcanii. [PDF]

PLoS Genet
Nußbaum P, Grünberger F, Neuschütz F, Chou K, Sivabalasarma S, Eulitz A, Sailer AL, Vogl K, Exterkate M, He W, Marchfelder A, Grohmann D, Albers SV.   +12 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

The Association Between the Progressive Motility of Bovine Spermatozoa and the Developmental Morphokinetics of In Vitro-Derived Embryos. [PDF]

J Dev Biol
Maizus S, Kalo D, Kogan T, Michaelov A, Roth Z.   +4 more
europepmc   +1 more source

Bacterial Motility [PDF]

Journal of Bacteriology, 1934
E O, Jordan, M E, Caldwell, D, Reiter
openaire   +2 more sources

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Effects of Epimedium supplementation on post-thaw spermatological and oxidative stress parameters in bull semen. [PDF]

Trop Anim Health Prod
Gökdemir T, Önder NT, Kiliç MC, Şahi̇n O, Başer L, Öztürkler Y, Yıldız S.   +6 more
europepmc   +1 more source