Results 51 to 60 of about 857,613 (315)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
ObjectiveEquinus foot deformity (EFD) is the most common deformity following a stroke. Several approaches have been suggested for its correction, including pharmacological, surgical, and physical therapy (PT) interventions.
Isabella Campanini +9 more
doaj +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
A toolset for the analysis and optimization of motion estimation algorithms and processors [PDF]
This paper presents a reconfigurable processor designed to execute user-defined block-matching motion estimation algorithms, and a toolset for the design of such algorithms and for the configuration of the processor.
Spiteri, T +5 more
core +1 more source
Aggregation Periods Influence Step Count Error in Low-Power Wearables
Wearable sensors are increasingly used to monitor physical activity, yet low-power devices often rely on data aggregation to conserve battery life, potentially impacting measurement accuracy.
Sydney Lundell, Kenton R. Kaufman
doaj +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Mechanical Method for Rapid Determination of Step Count Sensor Settings
With the increased push for personalized medicine, researchers and clinicians have begun exploring the use of wearable sensors to track patient activity.
Sydney Lundell, Kenton R. Kaufman
doaj +1 more source
Stability Control of a Biped Robot on a Dynamic Platform Based on Hybrid Reinforcement Learning
In this work, we introduced a novel hybrid reinforcement learning scheme to balance a biped robot (NAO) on an oscillating platform, where the rotation of the platform is considered as the external disturbance to the robot. The platform had two degrees of
Ao Xi, Chao Chen
doaj +1 more source

