Results 71 to 80 of about 23,735,145 (303)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
, 2021 Análise de movimento é actualmente um tópico de pesquisa bastante activo nas áreas da Visão por Computador, Computação Gráfica e Biomecânica, devido `a sua aplicabilidade num vasto espectro de aplicações em diversas áreas.
Moreira, Pedro Miguel +2 more
core +1 more source
Local and Global Models for Articulated Motion Analysis [PDF]
, 2006 Vision is likely the most important of the senses employed by humans in understanding their environment, but computer systems are still sorely lacking in this respect.
Wagg, David Kenneth, Wagg, David K
core +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Motion Extrapolation via Human Motion Analysis
, 2011 100學年度許輝煌升等參考著作We propose a novel motion analysis algorithm by using the mean-shift segmentation and motion estimation technique. Mean shift algorithm is frequently used to extract objects from video according to its efficiency and robustness of non ...
Tsai, Joseph C.; Hsu, Hui-Huang; Chang, Shih-Ming; Wang, Ying-Hong; Chao, Chia-Cheng; Shih, Timothy K.
core
Frontiers in NeurologyIntroductionPatients with Charcot–Marie–Tooth disease (CMT) often suffer from walking-related pain (WRP), muscle weakness, foot deformities, and reduced ankle dorsiflexion (DF), which affects their ability to walk and daily activities. Functional surgery
Giacomo Basini +10 more
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Two-Dimensional Motion Perception in Flies [PDF]
, 1993 Borst A, Egelhaaf M, Seung HS. Two-Dimensional Motion Perception in Flies. Neural Computation. 1993;5(6):856-868.We study two-dimensional motion perception in flies using a semicircular visual stimulus.
Egelhaaf, M. +8 more
core +1 more source