Results 101 to 110 of about 3,006,826 (294)
Motion event and deictic motion verbs as path-conflating verbs [PDF]
, 2006 This paper attempts to decompose the Motion event into such elements as Figure, Path, Vector, and Ground based upon Talmy\u27s framework, which makes it possible to formally analyze and compare the lexical semantics of the deictic motion verbs within and
Nakazawa, Tsuneko
core +1 more source
Pluractional Motion Verbs in Turkish
LanguagesIn this paper, we examine a small set of motion verbs in Turkish bearing the so-called ‘reciprocal’ suffix -(I)ş: kaç-ış- ‘flee in all directions’ (cf. kaç- ‘flee’), koş-uş- ‘run helter-skelter’ (cf. koş- ‘run’), uç-uş- ‘fly helter-skelter’ (cf. uç- ‘fly’
Greg Key, Eszter Ótott-Kovács
doaj +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Cognitive LinguisticsThis study explores the diachronic development of the Mandarin complex directional complement guòlái ‘come over’ from the macro-event perspective. By analyzing data retrieved from the CCL corpus spanning 15 Chinese dynasties (1046 BCE-1920s), this study ...
Yang Yuhang, Li Fuyin Thomas
doaj +1 more source
Process Before Events: An Ontology of Motion and Spacetime
PhilosophiesThis paper develops a process ontology of spacetime grounded in the primacy of motion. Standard interpretations of relativity are commonly understood in terms of a four-dimensional manifold of events, with motion represented by world-lines connecting ...
Ori Belkind
doaj +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source