Results 91 to 100 of about 457,293 (369)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Time-domain hydrodynamic analysis of pontoon-plate floating breakwater

open access: yesWater Science and Engineering, 2012
The hydrodynamic behaviors of a floating breakwater consisting of a rectangular pontoon and horizontal plates are studied theoretically. The fluid motion is idealized as two-dimensional linear potential flow.
Zhi-jie Chen   +3 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Numerical Study on the Influence of Interceptor and Stern Flap on Ship Resistance and Motion Response in Regular Waves

open access: yesJournal of Marine Science and Engineering
Stern flaps and interceptors are prevalent stern appendages on medium- to high-speed ships, designed to modify the sailing posture of ships and diminish resistance.
Kewei Song   +5 more
doaj   +1 more source

The Simultaneous Assessment of Time and Motion Response during Dual Tasks. [PDF]

open access: yesSensors (Basel), 2023
Flavia M   +5 more
europepmc   +1 more source

Influence of ground motion scaling on floor response spectra

open access: diamond, 2023
S. P. Challagulla   +4 more
openalex   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Transient and steady-state response properties of movement detectors

open access: yes, 1989
Egelhaaf M, Borst A. Transient and steady-state response properties of movement detectors. Journal of the Optical Society of America, A: Optics, Image Science, and Vision.
Egelhaaf, M.   +3 more
core   +1 more source

Structural design and motion response of parallelogram hydraulic support in pitching oblique mining face of steeply dipping coal seam

open access: yesMeitan kexue jishu
The hydraulic support is the core of the stability of the ‘surrounding rock and equipm ent’ system in the pitching oblique working face of steeply dipping coal seam.
Yongping WU   +7 more
doaj   +1 more source

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