Results 71 to 80 of about 396,992 (267)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Numerical Study on the Influence of Interceptor and Stern Flap on Ship Resistance and Motion Response in Regular Waves

Journal of Marine Science and Engineering
Stern flaps and interceptors are prevalent stern appendages on medium- to high-speed ships, designed to modify the sailing posture of ships and diminish resistance.
Kewei Song, Jie Gong, Jincun Ma, Qiang Xu, Yue Shi, Feng Xu   +5 more
doaj   +1 more source

Is facilitation responsible for the “motion induction” effect?

Vision Research, 1997
When a horizontal bar is presented after a single dot is shown at one of its ends, an illusory motion is seen which has been dubbed "motion induction" in the literature. The phenomenon has been attributed to a facilitation process which asymmetrically modulates the inputs to motion detectors, for instance by some sort of changes in processing speed ...
openaire   +2 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Structural design and motion response of parallelogram hydraulic support in pitching oblique mining face of steeply dipping coal seam

Meitan kexue jishu
The hydraulic support is the core of the stability of the ‘surrounding rock and equipm ent’ system in the pitching oblique working face of steeply dipping coal seam.
Yongping WU, Yuqian DU, Panshi XIE, Hongwei WANG, Bosheng HU, Zhuangzhuang YAN, Tong WANG, Tao HU   +7 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Comparision of Integrated Towing Motion Performance for Multi-Column Semisubmersible Floating Offshore Wind Turbines

南方能源建设
[Introduction] A comparative research was conducted to investigate the variation rules of motion responses in various degrees of freedom (DOF) and towline forces in the towing process of three-column submerged floating offshore wind turbines (TC-SFOWT ...
Xiling QI, Conghuan LE, Jianyu REN, Puyang ZHANG, Hongyan DING, Xiaoliang QI   +5 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Study on the Prediction of Motion Response of Offshore Platforms Based on ResCNN-LSTM

Journal of Marine Science and Engineering
In the random sea environment, offshore platforms are influenced by factors such as wind, waves, and currents, as well as their interactions, leading to complex motion phenomena that affect the safety of offshore platform operations.
Feng Diao, Tianyu Liu, Franck Aurel Likeufack Mdemaya, Gang Xu   +3 more
doaj   +1 more source

Optimizing of trimaran motion response based on Monto Carlo method

Zhongguo Jianchuan Yanjiu, 2019
[Objectives]To study the influence of side-hull layout of trimaran on its motion performance,[Methods]A new method which is based on Monte Carlo method and potential flow theory is presented to help side-hull layout of trimaran optimize its motion and ...
Wang Shuo, Zong Zhi
doaj   +1 more source