Results 81 to 90 of about 457,293 (369)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

A LQR washout algorithm for a driving simulator equipped with a hexapod platform : the relationship of neuromuscular dynamics with the sensed illness rating [PDF]

, 2012
This study proposes a method and an experimental validation to analyze dynamics response of the drivers with respect to the type of the control used in the hexapod driving simulator.
KEMENY, Andras, MERIENNE, Frédéric, AYKENT, Baris, PAILLOT, Damien   +3 more
core  

Outdoor performance of a motion-sensitive neuron in the blowfly

, 2001
Egelhaaf M, Grewe J, Kern R, Warzecha A-K. Outdoor performance of a motion-sensitive neuron in the blowfly. Vision research. 2001;41(27):3627-3637.We studied an identified motion-sensitive neuron of the blowfly under outdoor conditions.
Egelhaaf, Martin, Grewe, Jan, Anne-Kathrin Warzecha, Egelhaaf, Martin ; https://orcid.org/, Martin Egelhaaf, Kern, Roland ; https://orcid.org/, Kern, Roland, Roland Kern, Warzecha, Anne-Kathrin, Jan Grewe   +9 more
core   +1 more source

Motion sickness, stress and the endocannabinoid system [PDF]

, 2010
A substantial number of individuals are at risk for the development of motion sickness induced nausea and vomiting (N&V) during road, air or sea travel.
Kreth Simone, Feuerecker, Matthias, Matthias Feuerecker, Ines Kaufmann, Kaufmann, Ines, Kreth, Simone, Thieme, Detlef, Thieme Detlef, Choukèr Alexander, Schelling Gustav, Feuerecker Matthias, Michael Vogeser, Kaufmann Ines, Vogeser Michael, Manfred Thiel, Schelling, Gustav, Vogeser, Michael, Choukèr, Alexander, Detlef Thieme, Thiel, Manfred, Gustav Schelling, Alexander Choukèr, Daniela Hauer, Thiel Manfred, Hauer, Daniela, Simone Kreth, Hauer Daniela   +26 more
core   +1 more source

Motion Performance Analysis of Offshore Lifting for Wind-Fishery Integrated Aquaculture Net Cage Considering Multi-Body Coupling Effects

南方能源建设
[Objective] This study aims to investigate the multi-body hydrodynamic interaction mechanisms during offshore lifting operations of aquaculture net cages in wind-fishery integration systems.
Wanqi WANG, Tongshun YU, Peng LU, Hui ZHAO, Wei TAO   +4 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Responses of blowfly motion-sensitive neurons to reconstructed optic flow along outdoor flight paths

, 2005
Böddeker N, Lindemann JP, Egelhaaf M, Zeil J. Responses of blowfly motion-sensitive neurons to reconstructed optic flow along outdoor flight paths. J Comp Physiol A Neuroethol Sens Neural Behav Physiol.
Lindemann, Jens Peter ; https://orcid.org/, J. P. Lindemann, N. Boeddeker, J. Zeil, Egelhaaf, Martin ; https://orcid.org/, Böddeker, Norbert, Zeil, Jochen, M. Egelhaaf   +7 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Unaffected perceptual thresholds for biological and non-biological form-from-motion perception in autism spectrum conditions [PDF]

, 2010
Background: Perception of biological motion is linked to the action perception system in the human brain, abnormalities within which have been suggested to underlie impairments in social domains observed in autism spectrum conditions (ASC).
Blakemore, SJ, Ayse Pinar Saygin, Cook, J., Blakemore, S. J., Saygin, A. P., Cook Jennifer, Cook, Jennifer, Blakemore, S, Sarah-Jayne Blakemore, Blakemore, Sarah-Jayne, Saygin Ayse Pinar, Cook, J. L., Jennifer Cook, Saygin, Ayse Pinar, Blakemore, S.J., Cook, J, Saygin, AP, Saygin, A.P., Cook, JH, Blakemore Sarah-Jayne, Cook, Jennifer; id_orcid   +20 more
core   +1 more source