Results 51 to 60 of about 11,193,681 (316)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Study on hydrodynamic response characteristics of double moored floating box considering influence of connection stiffness and length

Zhongguo Jianchuan Yanjiu
Objective Articulated multiple floating structures are not only subject to wave excitation forces, but also to other nonlinear loads such as connection forces, mooring forces and diffraction forces between floats, making it challenging to predict their ...
Zhengyuan ZHANG, Chong WANG, Wei CHAI, Chunbao LI   +3 more
doaj   +1 more source

Experimental Investigation of Mooring Performance and Energy-Harvesting Performance of Eccentric Rotor Wave Energy Converter

Journal of Marine Science and Engineering, 2022
To obtain the optimal mooring mode and the best-matching wave condition of an eccentric rotor wave energy converter (ERWEC), a physical model of the ERWEC was developed. Ten mooring modes and eight wave conditions were set up.
Gang Xue, Jian Qin, Zhenquan Zhang, Shuting Huang, Yanjun Liu   +4 more
doaj   +1 more source

Distance in Motion: Response Trajectories Reveal the Dynamics of Number Comparison

PLoS ONE, 2011
Cognitive and neuroscientific evidence has challenged the widespread view that perception, cognition and action constitute independent, discrete stages. For example, in continuous response trajectories toward a target response location, evidence suggests
Seppe Santens, Sofie Goossens, Tom Verguts   +2 more
semanticscholar   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Priming with real motion biases visual cortical response to bistable apparent motion [PDF]

Proceedings of the National Academy of Sciences, 2012
Apparent motion quartet is an ambiguous stimulus that elicits bistable perception, with the perceived motion alternating between two orthogonal paths. In human psychophysical experiments, the probability of perceiving motion in each path is greatly enhanced by a brief exposure to real motion along that path.
Qing-fang, Zhang, Yunqing, Wen, Deng, Zhang, Liang, She, Jian-young, Wu, Yang, Dan, Mu-ming, Poo   +6 more
openaire   +2 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Wave Motion Response Analysis of Flip-Type Ocean Aquaculture Platforms Based on AQWA

Journal of Marine Science and Engineering
The stability of deep-sea aquaculture equipment under extreme sea conditions such as typhoons directly affects the safety and operational reliability of the aquaculture platform, which in turn affects the economic benefits of fish farming.
Hongling Qin, Li Peng, Zhiyuan Wang, Siqi Wu, Wei He, Yuanping Yang, Jian Li, Hao Zhang   +7 more
doaj   +1 more source

Towing Operation Methods of Offshore Integrated Meteorological Mast for Offshore Wind Farms

Journal of Marine Science and Engineering, 2019
An offshore integrated meteorological mast (OIMM) is introduced which has great application potential for the development of offshore wind turbine power.
Hongyan Ding, Ruiqi Hu, Conghuan Le, Puyang Zhang   +3 more
doaj   +1 more source

Orientation and Direction-of-Motion Response in the Middle Temporal Visual Area (MT) of New World Owl Monkeys as Revealed by Intrinsic-Signal Optical Imaging

Frontiers in Neuroanatomy, 2010
Intrinsic-signal optical imaging was used to evaluate relationships of domains of neurons in middle temporal visual area (MT) selective for stimulus orientation and direction-of-motion.
P. Kaskan, B. Dillenburger, Haidong D. Lu, A. W. Roe, J. Kaas   +4 more
semanticscholar   +1 more source