Results 31 to 40 of about 4,207,968 (311)

Motivation Peer Training – Bridging the gap for people with mobility disabilities

open access: yesAfrican Journal of Disability, 2017
Background: Only 2% of people with disabilities in developing countries have access to basic services and rehabilitation. Objectives: To bridge this gap, Motivation has been running Peer Training activities since 1993 and has identified that there is a ...
Lucy K. Norris
doaj   +1 more source

Directives, expressives, and motivation [PDF]

open access: yes, 2017
When an agent’s motivation is sensitive to how his supervisor thinks about the agent’s competence, the supervisor has to take into account both informational and expressive contents of her message to the agent.
Suzuki, Toru
core   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Convergent direct and indirect cortical streams shape avoidance decisions in mice via the midline thalamus

open access: yesNature Communications
Current concepts of corticothalamic organization in the mammalian brain are mainly based on sensory systems, with less focus on circuits for higher-order cognitive functions.
Jun Ma   +6 more
doaj   +1 more source

Neuro-computational account of how mood fluctuations arise and affect decision making

open access: yesNature Communications, 2018
Fluctuations in mood are known to affect our decisions. Here the authors propose and validate a model of how mood fluctuations arise through a slow integration of positive and negative feedback and report the resulting key changes in brain activity that ...
Fabien Vinckier   +3 more
doaj   +1 more source

Controllability Attribution as a Mediator in the Effect of Mindset on Achievement Goal Adoption Following Failure

open access: yesFrontiers in Psychology, 2020
The purpose of this study was to examine the effect of a growth mindset on achievement goal adoption in the face of failure. We also sought to investigate the mediating role of controllability attribution in order to understand the underlying process ...
Juyeon Song, Sung-il Kim, Mimi Bong
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Musical Motivation: Towards a model synthesising the research [PDF]

open access: yes, 2002
This article explores motivation to participate in music making activities. It examines historical and current theories of motivation and sets out a model describing the way that the characteristics of the individual including, personality, self-concept ...
Hallam, Susan
core   +3 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Exploring individual biases in BCI research and users: Does gender matter?

open access: yesFrontiers in Human Neuroscience
ObjectiveBrain-Computer Interface (BCI) is an interdisciplinary research field characterized by rapid technological advances and collaborative efforts to develop user-friendly, adaptive devices that enable healthy and non-responsive users to communicate ...
Cornelia Herbert   +3 more
doaj   +1 more source

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