Results 41 to 50 of about 786,998 (248)
Adolescents, menstruation, and physical activity: insights from a global scoping review
BMC Women's HealthBackground Adolescent girls tend to be less physically active than boys, a trend that coincides with puberty. Menstruation may act as a barrier to physical activity, which in turn may influence menstrual symptoms.
Jessica Harvey +8 more
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
How mood-related physiological states bias economic decisions
Communications PsychologyWhen making decisions, humans are susceptible to all sorts of biases, relative to rational norms. An important factor is incidental changes in affective states, such as variations in mood between happiness and sadness.
Roeland Heerema, Mathias Pessiglione
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The Influence of Identity Within-Person and Between Behaviours: A 12-Week Repeated Measures Study
Behavioral SciencesPeople act in ways that align with the values and roles that constitute their identity. However, the consistency of identity’s influence across different behaviours, and whether identity influences behaviours directly or indirectly via intention, self ...
Kristie-Lee R. Alfrey +2 more
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Journal of Education, Health and Sport, 2017 Urmański Jan, Wac Katarzyna. Świadomość i przekonania ojców na temat współczesnych zagrożeń i bezpieczeństwa dzieci = The awareness and conviction of the fathers on contemporary risks and safety of children. Journal of Education, Health and Sport. 2016;6(
Jan Urmański, Katarzyna Wac
doaj +3 more sources
Motivation Regarding Physical Exercise among Health Science University Students [PDF]
, 2022 Susana Sánchez Herrera +3 more
openalex +1 more source
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Molecular Oncology, EarlyView.Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source
Absence of covert face valuation in Autism
Translational Psychiatry, 2021 Autism is a neurodevelopmental condition defined on clinical criteria related to diminished social reciprocity and stereotyped behavior. An influential view explains autism as a social motivation disorder characterized by less attention paid to the ...
Fabien Vinckier +2 more
doaj +1 more source