Results 101 to 110 of about 862,527 (298)
The strategic motive to sell forward: experimental evidence [PDF]
, 2009 We test the strategic motive to sell forward in experimental Cournot duopoly and quadropoly environments with either a finite (exogenous close) or an infinite (endogenous close) number of forward markets.
Ferreira, José Luis +2 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
IS THE PROFIT MOTIVE AN IMPORTANT DETERMINANT OF GRAZING LAND USE AND RANCHER MOTIVE? [PDF]
We build our economic models and estimate grazing policy impacts based on the standard economic model of profit maximization. Yet, over 30 years of research and observation has shown that, for many, consumptive and quality of life values are the most ...
Bailey, Scott A., Torell, L. Allen
core +1 more source
, 2020 In this article, we study the Gross-Schoen diagonal cycle on the triple product of Shimura curves at a place of good reduction. We prove the unramified arithmetic level raising theorem for triple product of Shimura curves and we deduce from it the second
Wang, Haining
core
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
MOTIVATION OF STUDENTS TO LEARN: SOCIAL AND PSYCHOLOGICAL ASPECT
Вестник университета, 2019 Now a serious social and psychological problem of motivation to training is the fact that students «at any cost» and on any terms are necessary for higher education institutions.
N. Gerasimenko
doaj
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Democritus and the motive power of fire
, 2011 The present work is a translation from french to english of our previous \g{D\'emocrite et la puissance motrice du feu}, amended on a number of respects. It is mainly of historical and pedagogical interest.
Arnaud, Jacques +2 more
core +2 more sources
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source