Results 81 to 90 of about 141,166 (265)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
The theme of the North in modern Russian folk-horror
RUDN Journal of Studies in Literature and JournalismExamines the specifics of the implementation of the North theme in the subgenre of modern domestic folk horror using the example of novels and stories by D. Bobyleva, O. Kozhin, L. Lvova, A. Podolsky, M. Romanova.
Elena A. Safron
doaj +1 more source
Puppet Motive in the Novel by D. Rubin «Punch’s Syndrome»
, 2015 The article is devoted to the puppet motive in the novel by D. Rubin «Punch’s Syndrome». The author analyzes the forms and methods of representation of this motive on different levels of the novel: conceptual, compositional, narrative, figurative; the ...
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
M. Yu. Lermontov’s “The Cliff”: Motive of Loneliness in the Structure of the Text
Известия Южного федерального университета: Филологические науки, 2019 It is shown that in the poem a number of folklore and mythological (including universal) images and plots are significant – the world tree, the tale of the firebird, the myth of Cupid and Psyche.
Oleg B. Zaslavsky
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Intra-family Transfers in Japan: Intergenerational Co-residence, Distance, andContact [PDF]
Classified broadly, two motives for intra-family transfers exist: altruism and selfishness. This paper examines two selfish hypotheses | the exchange motive (strategic bequest motive)and the demonstration effect | using a new Japanese micro data set.
Ken Yamada
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
The Competitive Saving Motive: Evidence from Rising Sex Ratios and Savings Rates in China [PDF]
The high and rising household savings rate in China is not easily reconciled with the traditional explanations that emphasize life cycle factors, the precautionary saving motive, financial development, or habit formation.
Shang-Jin Wei, Xiaobo Zhang
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Spätmittelalterliche reliefierte Ofenkeramik in Bern. Herstellung und Motive [PDF]
, 1994 Die vorliegende Publikation befasst sich umfassend mit den mittelalterlichen Ofenkacheln, die bis 1992 in Bern gefunden wurden. In der Art eines Nachschlagewerkes gibt die Publikation mit den zahlreichen Fundtafeln einen Überblick über die verschiedenen ...
Gutscher, Daniel +2 more
core +1 more source