Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
M. Yu. Lermontov’s «Terek gifts»: Contradictions as a Structural Basis of the World
It is given the analysis of «Terek’s gifts» as an integral work. Structural comparison of stories with three gifts is carried out. It is pointed out the poem’s invariant, it is the double structure in which opposites are combined (top - bottom, dying ...
Oleg B. Zaslavsky
doaj +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Sacral Geography as a System: Problem of Sacral Object’s Status
The author proposes to consider the revered loci of a particular area as a system, the elements of which are not isolated from each other, but demonstrate the relationship.
A. P. Lipatova
doaj +1 more source
The pay-as-you-go pension system as fertility insurance and an enforcement device [PDF]
A PAYGO system may serve as insurance against not having children and as an enforcement device for ungrateful children who are unwilling to pay their parents a pension. In fact, the latter was Bismarck’s historic motive for introducing this system. It is
Sinn, Hans-Werner
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
The pedagogical analysis of diagnostics of students of the legal institute visiting discipline "physical training". [PDF]
It is considered that during educational process it is very important to generate correct understanding of a healthy way of life in consciousness of students and to impart it skills and ability of preventive maintenance of diseases.
Popichev M.I.
doaj
Phenomenon of Transfiguration and System of Motifs in I. S. Shmelev’s Story “The Kulikovo Field”
The article presents an analysis of motives that permeate the narrative in the story by Ivan Shmelev “The Kulikovo Field.” The author identified a number of motives, which semantics and functioning is interpreted at subject-figurative, symbolic, thematic
E. V. Paraskeva
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Disentangling the Importance of the Precautionary Saving Motive [PDF]
We evaluate the importance of the precautionary saving motive by relying on a direct question about precautionary wealth from the 1995 and 1998 waves of the Survey of Consumer Finances.
Annamaria Lusardi, Arthur Kennickell
core

