Results 51 to 60 of about 862,527 (298)
Sociological research of families, having children time-lagged motive development [PDF]
Pedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2010 Attitude of monogynopaedium is rotined toward the delay of motive development of their child, willingness actively to co-operate with the command of specialists on the program of early interference.
Nagorna O. B.
doaj
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
CHARACTERIZATION THE DEVELOPMENT OF THE MOTIVE SPHERE IN SCHOOLCHILDREN WITH MENTAL RETARDATION
Ra Ximhai, 2016 The characterizationof schoolchildrenwithspecial educationalneedsis one ofthe researcheswhich areprioritized by theLatin American Reference Centerfor Special Education.
Lissette María Hernández-Martínez
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CHAMBER VOCAL CREATIONS BY SNEJANA PÎSLARI: GENERAL CHARACTERISTICS, GENRE AND STYLE FEATURES [PDF]
Studiul Artelor şi Culturologie: Istorie, Teorie, Practică, 2016 The author suggests a general characterization of the chamber vocal creations by Snejana Pîslari. The present work represents a detailed analysis of the romances, written by the composer on lyrics by M. Eminescu and N. Labiş. The author reveals the genre
COADĂ TATIANA
doaj
Communication & Society (Formerly Comunicación y Sociedad), 2019 The student movement has always been at the centre of political change in Chile, which has resulted in tensions with the heavily monopolized media.
Carolina Pérez-Arredondo
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M. Yu. Lermontov’s «Terek gifts»: Contradictions as a Structural Basis of the World
Известия Южного федерального университета: Филологические науки, 2020 It is given the analysis of «Terek’s gifts» as an integral work. Structural comparison of stories with three gifts is carried out. It is pointed out the poem’s invariant, it is the double structure in which opposites are combined (top - bottom, dying ...
Oleg B. Zaslavsky
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source