Results 31 to 40 of about 61,290 (219)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Motivations for substance abusers: A qualitative study
مجله علوم روانشناختی, 2021 Background: Substance abuse represents one of the major concerns in developing countries such as Iran. On the other hand, most previous research has been on the motivations for substance abuse in local samples and younger age groups (eg adolescents), and
Hassan Mokhtarpour +3 more
doaj
Неофилология, 2021 We analyze the process of appearance and approval of orphanhood motive in V. Astafyev’s work. We substantiate its connection with autobiographical episodes from the prosaist’s life.
V. A. Tscherbakova, P. A. Goncharov
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Sociological research of families, having children time-lagged motive development [PDF]
Pedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2010 Attitude of monogynopaedium is rotined toward the delay of motive development of their child, willingness actively to co-operate with the command of specialists on the program of early interference.
Nagorna O. B.
doaj
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
M. Yu. Lermontov’s «Terek gifts»: Contradictions as a Structural Basis of the World
Известия Южного федерального университета: Филологические науки, 2020 It is given the analysis of «Terek’s gifts» as an integral work. Structural comparison of stories with three gifts is carried out. It is pointed out the poem’s invariant, it is the double structure in which opposites are combined (top - bottom, dying ...
Oleg B. Zaslavsky
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Communication & Society (Formerly Comunicación y Sociedad), 2019 The student movement has always been at the centre of political change in Chile, which has resulted in tensions with the heavily monopolized media.
Carolina Pérez-Arredondo
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source