Results 41 to 50 of about 59,454 (269)

Functions of the anthroponyms in the novels by Dina Rubina “Belaya golubka Kordovy” (The white dove of Cordoba”) and “Sindrom Petrushki” (The Punch Syndrome)

RUDN Journal of Studies in Literature and Journalism, 2018
The article is devoted to the anthroponym function of the name “Silva” in two novels by Dina Rubina: “Belaya golubka Kordovy” (“The white dove of Cordoba”, 2009) and “Sindrom Petrushki” (“The Punch Syndrome”, 2010).
Lyubov’ Gennadyevna Kikhney, Alina Georgievna Silcheva   +1 more
doaj   +1 more source

Ethical Traditions of Adyghe: Genre Criteria and Main Motives

Научный диалог, 2021
The task is to study ethical legends considered as one of the specific genre varieties of the Adyghe historical prose. The relevance of the research is due to the urgent need to create a genre classification of the Adyghe non-fairytale prose. It is noted
Z. Zh. Kudaeva, K. N. Paranuk, A. P. Golodova   +2 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Motivations for substance abusers: A qualitative study

مجله علوم روانشناختی, 2021
Background: Substance abuse represents one of the major concerns in developing countries such as Iran. On the other hand, most previous research has been on the motivations for substance abuse in local samples and younger age groups (eg adolescents), and
Hassan Mokhtarpour, Mohammad Ali Goodarzi, Mohammad Reza Taghavi, Aliakbar Faghihi   +3 more
doaj  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Sociological research of families, having children time-lagged motive development [PDF]

Pedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2010
Attitude of monogynopaedium is rotined toward the delay of motive development of their child, willingness actively to co-operate with the command of specialists on the program of early interference.
Nagorna O. B.
doaj  

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source