Results 111 to 120 of about 281,251 (358)

Motivating Motives

open access: yes
Underlying the Riemann Hypothesis there is a question whose full answer still eludes us: what do the zeros of the Riemann zeta function really mean? As a step toward answering this, André Weil proposed a series of conjectures that include a simplified version of the Riemann Hypothesis in which the meaning of the zeros becomes somewhat easier to ...
openaire   +2 more sources

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Generic motives and motivic cohomology of fields

open access: yes
International audienceThis paper investigates the structure of generic motives and their implications for the motivic cohomology of fields. Originating in Voevodsky's theory of motives and related to Beilinson's vision of a motivic t-structure, generic ...
Déglise, Frédéric
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Quantity Competition, Endogenous Motives and Behavioral Heterogeneity [PDF]

open access: yes
The paper shows that strategic quantity competition can be characterized by behavioral heterogeneity, once competing firms are allowed in a pre-market stage to optimally choose the behavioral rule they will follow in their strategic choice of quantities.
Chirco, Alessandra   +2 more
core  

Promoting breastfeeding through the analysis of the motives and barriers of the target audience

open access: yesResponsibility and Sustainability, 2014
Despite the well-known beneficial effects of breastfeeding on children’s health, there are always threatening alternatives over this desired mothers’ conduct.
Gonzalo Díaz-Meneses   +1 more
doaj  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Mixed Motives of Simultaneous-move Games in a Mixed Duopoly [PDF]

open access: yes
This paper investigates the simultaneous-move games in a mixed duopoly where firms are maximizers of either profits or relative profits. Contrary to previous results, if each firm has mixed motives about payoff in a simultaneous-move game, a private firm
Kangsik Choi
core  

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Savings motives and the effectiveness of tax incentives – an analysis based on the demand for life insurance in Germany [PDF]

open access: yes
We exploit data on German households’ savings in life insurance products, the characteristics of life insurance products and the specific tax treatment of savings in life insurance products to assess the importance of different savings motives and the ...
Mathias Sommer
core  

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