Results 131 to 140 of about 281,251 (358)
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
On the Chow ring of certain Fano fourfolds
Annales Universitatis Paedagogicae Cracoviensis: Studia Mathematica, 2020 We prove that certain Fano fourfolds of K3 type constructed by Fatighenti–Mongardi have a multiplicative Chow–Künneth decomposition. We present some consequences for the Chow ring of these fourfolds.
Robert Laterveer
doaj
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
Motives for parental money transfers in Europe. [PDF]
We find a high prevalence of Europeans giving equal financial transfers to their adult children, regardless of siblings’ income differences. This behaviour is sharply different from previously documented for American counterparts and it is not predicted ...
Olivera Angulo, Javier
core +2 more sources
Heavy-Light Wall Crossings and Motivic Asymptotics of Moduli Spaces of Curves. Part I: Stabilization Graphs and Euler Characteristics [PDF]
Giordano Cotti
openalex +1 more source
The multifaceted roles of lysosomes in cancer
Molecular Oncology, EarlyView.Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source
DiSlawIn the context of the variety of search options in the Slovenian corpus Nova Beseda, predominantly positively connoted adjectives with the word motivation are found. The concordance shows that motivation occurs most frequently in certain occupational groups.
openaire +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source