Results 151 to 160 of about 120,404 (262)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

The impact of the experimental "Hypoxic Boxing" training on the motor abilities and specialized fitness of national boxing champions: a randomized controlled trial. [PDF]

Front Physiol
Ambroży T, Snopkowski P, Rydzik Ł, Kędra A, Wąsacz W.   +4 more
europepmc   +1 more source

A Study about a New Standardized Method of Home-Based Exercise in Elderly People Aged 65 and Older to Improve Motor Abilities and Well-Being: Feasibility, Functional Abilities and Strength Improvements. [PDF]

Geriatrics (Basel), 2022
Melchiorri G, Triossi T, Viero V, Marroni S, D'Arcangelo G, Tancredi V.   +5 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Differences in anthropometric characteristics and motor abilities of professional football players from leading and average teams in Serbian super league. [PDF]

BMC Sports Sci Med Rehabil
Radakovic R, Majkic B, Katanic B, Govindasamy K, Veljkovic AA, Băltean AI, Geantă VA.   +6 more
europepmc   +1 more source

Automated scoring for a Tablet-based Rey Figure copy task differentiates constructional, organisational, and motor abilities. [PDF]

Sci Rep, 2021
Petilli MA, Daini R, Saibene FL, Rabuffetti M.   +3 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Effect of an adapted Taekwondo-based intervention on functional and motor abilities in elderly care home residents: a study protocol. [PDF]

BMJ Open Sport Exerc Med
Senesi G, Scoppolini Massini M, Zinno R, Davalli A, Romano L, Barone G, Pinelli E, Bragonzoni L.   +7 more
europepmc   +1 more source

Relationships between Gross Motor Abilities and Sensory Processing in Children Aged 18 to 36 Months. [PDF]

Phys Ther Res, 2021
Takahashi E, Nitta O, Takaki K, Toba Y.
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source