Results 131 to 140 of about 11,248,254 (342)

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Efeitos de um programa de jogos pré-desportivos nos aspectos psicobiológicos de idosas

Revista Brasileira de Geriatria e Gerontologia
OBJETIVO: Investigar o efeito de um programa de jogos pré-desportivos (JPD) nos aspectos psicobiológicos de idosas. MÉTODOS: 53 voluntárias idosas foram distribuídas em dois grupos: grupo Ativo (n=27) - submetido a um programa de JPD composto por ...
Irene Guarido Luz Bittar, Ricardo Luis Fernandes Guerra, Fabíola Cristina Lopes, Marco Túlio de Mello, Hanna Karen Moreira Antunes   +4 more
doaj   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

THE EFFECT OF PICROTOXIN ON MOTOR ACTIVITY AND THE ELECTROENCEPHALOGRAM OF MICE [PDF]

, 1965
Peter W. Ramwell, Jane E. Shaw
openalex   +1 more source

Puckered and JNK signaling in pioneer neurons coordinates the motor activity of the Drosophila embryo. [PDF]

Nat Commun, 2023
Karkali K, Vernon SW, Baines RA, Panayotou G, Martín-Blanco E.   +4 more
europepmc   +1 more source

Depresjon: a motor activity database of depression episodes in unipolar and bipolar patients

ACM SIGMM Conference on Multimedia Systems, 2018
Enrique Garcia-Ceja, M. Riegler, P. Jakobsen, J. Tørresen, T. Nordgreen, K. Oedegaard, O. B. Fasmer   +6 more
semanticscholar   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Quality of life and functional fitness of the elderly

Biomedical Human Kinetics, 2011
Leś Anna, Gaworska Marta
doaj   +1 more source

Sciatic Nerve Activity evoked by Sensory-motor Cortex Stimulation during Paradoxical Sleep [PDF]

, 1966
F. Baldissera, M Mancia
openalex   +1 more source

Inflammation Effects on Motivation and Motor Activity: Role of Dopamine

Neuropsychopharmacology, 2017
J. Felger, M. Treadway
semanticscholar   +1 more source