Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric+11 more
wiley +1 more source
Este estudo seccional teve por objetivo estimar o nível de atividade física (NAF) de idosos que frequentam centros de convivência (CCI), analisando a possível associação com quedas acidentais e outras variáveis relacionadas.
Priscila Carneiro Valim-Rogatto+2 more
doaj +1 more source
PERSISTENT TIDAL CYCLES OF SPONTANEOUS MOTOR ACTIVITY IN THE FIDDLER CRAB, UCA PUGNAX
Miriam F. Bennett+2 more
openalex +2 more sources
THE EFFECT OF PICROTOXIN ON MOTOR ACTIVITY AND THE ELECTROENCEPHALOGRAM OF MICE [PDF]
Peter W. Ramwell, Jane E. Shaw
openalex +1 more source
Patterns of physiological activity accompanying performance on a perceptual motor task. [PDF]
Richard I. Thackray
openalex +1 more source
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen+17 more
wiley +1 more source
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas+15 more
wiley +1 more source
The effects of osmotic pressure changes on the spontaneous activity at motor nerve endings
E. J. Furshpan
openalex +2 more sources
Behavioral states and state related heart rate and motor activity patterns in the newborn infant and the fetus antepartum — A comparative study. I. Technique, illustration of recordings, and general results [PDF]
H. D. Junge
openalex +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park+6 more
wiley +1 more source