Results 81 to 90 of about 266,743 (342)

Young Children’s cliques : a study on processes of peer acceptance and cliques aggregation [PDF]

, 2015
A considerable amount of research has examined the link between children’s peer acceptance, which refers to the degree of likability within the peer group, social functioning and emotional wellbeing, at a same age and in a long term perspective ...
Brighi, Antonella, Guarini, Annalisa, Mazzanti, Chiara, Sansavini, Alessandra   +3 more
core  

Calibration and Cross-Validation of Accelerometery for Estimating Movement Skills in Children Aged 8-12 Years [PDF]

, 2020
This study sought to calibrate triaxial accelerometery, worn on both wrists, waist and both ankles, during children’s physical activity (PA), with particular attention to object control motor skills performed at a fast and slow cadence, and to cross ...
Clark, Cain C T, Dobell, Alexandra, Duncan, Michael J, Eyre, Emma L J, Faghy, Mark A, Noon, Mark, Roscoe, Clare M P, Sacko, Ryan, Stodden, David   +8 more
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

How young children understand electric circuits: prediction, explanation and exploration [PDF]

, 2009
This paper reports findings from a study of young children’s views about electric circuits. Twenty- eight children aged 5 and 6 were interviewed. They were shown examples of circuits and asked to predict whether they would work and explain why. They were
Glauert, Esme
core   +6 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

The Relationship Between Motor Skills, Psychosocial Adjustment and Peer Victimization in School-Aged Children

Diversity of Research in Health Journal, 2018
The aim of this study was to investigate the relationships between childrens’ motor competence, psychosocial adjustment, peer victimization, physical activity participation and obesity.
Moriah Thorpe, Line Tremblay, Brahim Chebbi, Brahim Chebbi, Céline Larivière   +4 more
doaj   +1 more source

Ambiguities and paradoxes in a competence-based approach to vocational education and training in France [PDF]

, 2013
This article aims to show the effects of the prevalence of the competence regime within several sectors of vocational education and training in France.
Hébrard, Pierre
core   +2 more sources

Enhancing Motor Competence and Physical Activity in Kindergarten

Journal of Physical Activity and Health, 2019
This study aimed at evaluating the effect of the "Walk," an 8-month physical activity (PA) program led by classroom and physical education teachers, on the motor competence (MC) and PA of 5- to 6-year-old children.A total of 143 children (mean age = 61.51 [1.85] mo) participated in the study and were randomly assigned to the experimental and control ...
Aivazidis, D., Venetsanou, F., Aggeloussis, N., Gourgoulis, V., Kambas, A.   +4 more
openaire   +3 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source