Results 11 to 20 of about 253,081 (215)

A Pitx3-deficient developmental mouse model for fine motor, olfactory, and gastrointestinal symptoms of Parkinson's disease

Neurobiology of Disease, 2022
Parkinson's disease (PD) is characterized by the selective death of substantia nigra pars compacta (SNpc) dopaminergic neurons and includes both motor and non-motor symptoms.
Bin Song, Jacob W. Feldmann, Shibo Cao, Melissa Feitosa, Youngbin Kong, Woori Kim, Altana Schweitzer, Pierre Leblanc, Jeffrey S. Schweitzer, Kwang-Soo Kim   +9 more
doaj   +1 more source

Could the Urease of the Gut Bacterium Proteus mirabilis Play a Role in the Altered Gut–Brain Talk Associated with Parkinson’s Disease?

Microorganisms, 2023
Intestinal dysbiosis seems to play a role in neurodegenerative pathologies. Parkinson’s disease (PD) patients have an altered gut microbiota. Moreover, mice treated orally with the gut microbe Proteus mirabilis developed Parkinson’s-like symptoms.
Matheus V. C. Grahl, Brenda da Silva Andrade, Ana Paula A. Perin, Gilda A. Neves, Laura de Souza Duarte, Augusto Frantz Uberti, Kelvin Siqueira Hohl, Cristian Follmer, Celia Regina Carlini   +8 more
doaj   +1 more source

Cognitive and motor correlates of grey and white matter pathology in Parkinson’s disease

NeuroImage: Clinical, 2020
Introduction: Previous studies have found associations between grey matter atrophy and white matter hyperintensities (WMH) of vascular origin with cognitive and motor deficits in Parkinson’s disease (PD).
Mahsa Dadar, Myrlene Gee, Ashfaq Shuaib, Simon Duchesne, Richard Camicioli   +4 more
doaj   +1 more source

Motor impairments in Chinese toddlers with autism spectrum disorder and its relationship with social communicative skills

Frontiers in Psychiatry, 2022
ObjectiveMotor impairments are prevalent in children with autism spectrum disorder (ASD) and persistent across age. Our current study was designed to investigate motor deficits in Chinese toddlers with ASD and to explore the relationships between motor ...
Bingrui Zhou, Qiong Xu, Huiping Li, Ying Zhang, Dongyun Li, Ping Dong, Yi Wang, Ping Lu, Ye Zhu, Xiu Xu   +9 more
doaj   +1 more source

Persistent Motor Deficits in DAMP

Pediatric Neurology Briefs, 2000
Motor control in ability to perform everyday and spare-time activities was assessed at 11 to 12 years of age in 10 boys with deficits in attention, motor control and perception (DAMP) and compared with a group of 20 boys without DAMP.
J Gordon Millichap
doaj   +1 more source

Motor Deficits in the Ipsilesional Arm of Severely Paretic Stroke Survivors Correlate With Functional Independence in Left, but Not Right Hemisphere Damage

Frontiers in Human Neuroscience, 2020
Chronic stroke survivors with severe contralesional arm paresis face numerous challenges to performing activities of daily living, which largely rely on the use of the less-affected ipsilesional arm.
Shanie A. L. Jayasinghe, David Good, David A. Wagstaff, Carolee Winstein, Robert L. Sainburg, Robert L. Sainburg   +5 more
doaj   +1 more source

Disruption of rolandic gamma-band functional connectivity by seizures is associated with motor impairments in children with epilepsy. [PDF]

PLoS ONE, 2012
Although children with epilepsy exhibit numerous neurological and cognitive deficits, the mechanisms underlying these impairments remain unclear. Synchronization of oscillatory neural activity in the gamma frequency range (>30 Hz) is purported to be a ...
George M Ibrahim, Tomoyuki Akiyama, Ayako Ochi, Hiroshi Otsubo, Mary Lou Smith, Margot J Taylor, Elizabeth Donner, James T Rutka, O Carter Snead, Sam M Doesburg   +9 more
doaj   +1 more source

Asleep motor mapping in resected low-grade gliomas -a population based multicenter study

Brain and Spine
Introduction: Maximal safe resection is established goal of WHO grade 2 low-grade gliomas (LGG). Asleep motor mapping offers an alternative to awake surgery for tumors near motor areas and has been shown to be safe and effective in expert centers ...
Sophia M. Leiss, Margret Jensdottir, Ole Solheim, Alba Corell, Anna Lipatnikova, Sasha Gulati, Klas Holmgren, Francesco Latini, Ruby Mahesparan, Peter Milos, Alice Neimantaite, Henrietta Nittby Redebrandt, Lars Kjelsberg Pedersen, Rickard L. Sjöberg, Björn Sjögren, Gregor Tomasevic, Erik Thurin, Maria Zetterling, Jiri Bartek, Jr., Asgeir S. Jakola   +19 more
doaj   +1 more source

Rodent models of Parkinson’s disease: beyond the motor symptomatology

Frontiers in Behavioral Neuroscience, 2013
Parkinson's disease (PD) is classically characterized by motor symptoms; however, non-motor manifestations are increasingly recognized as relevant in this condition. Given the influence of these non-motor symptoms in the well-being of PD patients, it
Filipa Lopes Campos, Filipa Lopes Campos, Miguel M Carvalho, Miguel M Carvalho, Ana C Cristovão, Ana C Cristovão, Goun eJe, Graça eBaltazar, António J Salgado, António J Salgado, Yoon-Seong eKim, Nuno eSousa, Nuno eSousa   +12 more
doaj   +1 more source

Fine motor deficits in reading disability and language impairment: same or different? [PDF]

PeerJ, 2013
Several studies have found evidence of motor deficits in poor readers. There is no obvious reason for motor and literacy skills to go together, and it has been suggested that both deficits could be indicative of an underlying problem with cerebellar ...
Annie Brookman, Sarah McDonald, David McDonald, Dorothy V.M. Bishop   +3 more
doaj   +2 more sources