Results 181 to 190 of about 2,701,603 (305)

Identifying diagnostic biomarkers in functional motor disorders through multimodal behavioral, neurophysiological, and imaging assessment using explainable machine learning. [PDF]

J Neurol
Gandolfi M, Sandri A, Russo M, Sarasso E, Gardoni A, Basaia S, Erro R, Cuoco S, Carotenuto I, Ricciardi C, Amato F, Vinciguerra C, Botto A, Amboni M, Romano D, Di Vico IA, Fiorio M, Pedrotti G, Paolicelli A, Crestani M, Fratucello A, Mansueto G, Pizzini FB, Barillari M, Lauriola MF, Tozzi M, Rusciano F, Geroin C, Fasoli M, Marotta A, Salaorni F, Squintani GM, Mariotto S, Tamburin S, Paio F, De Biasi G, Piscosquito G, Zenere L, Canu E, Barone P, Filippi M, Agosta F, Pellecchia MT, Tinazzi M.   +43 more
europepmc   +1 more source

Going Beyond Conventional Assessment of Developmental Motor Disorders: Exploring Video Methods for Early Identification Among Children 0 to 3 Years. [PDF]

Adv Rehabil Sci Pract, 2023
Coxon ML, Hoyt CR, Smith AE, Hadders-Algra M.   +3 more
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Efficacy of transcutaneous auricular vagus nerve stimulation in treating patients with post-stroke motor disorders: a prospective study. [PDF]

Front Neurol
Xue R, Ma J.
europepmc   +1 more source

A 3D-printed passive exoskeleton for upper limb assistance in children with motor disorders: proof of concept through an electromyography-based assessment. [PDF]

PeerJ, 2023
Sanchez C, Blanco L, Del Río C, Urendes E, Costa V, Raya R.   +5 more
europepmc   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

The Spectrum of Motor Disorders in Patients with Chronic Kidney Disease: Pathogenic Mechanisms, Clinical Manifestations, and Therapeutic Strategies. [PDF]

J Clin Med
Jerzak P, Mizera J, Gołębiowski T, Kuriata-Kordek M, Banasik M.   +4 more
europepmc   +1 more source

Aberrant Auditory and Visual Memory Development of Children with Upper Limb Motor Disorders. [PDF]

Brain Sci, 2021
Koriakina M, Agranovich O, Petrova E, Kadieva D, Kopytin G, Ermolovich E, Moiseenko O, Alekseeva M, Bredikhin D, Bermúdez-Margaretto B, Ntoumanis I, Shestakova AN, Jääskeläinen IP, Blagovechtchenski E.   +13 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

The Complex Pathway of Conventional Investigations before the Diagnosis of Functional Motor Disorders. [PDF]

Mov Disord Clin Pract
Ercoli T, Geroin C, Marcuzzo E, Sandri A, Romito LM, Eleopra R, Tesolin L, de Bertoldi F, Nicoletti A, Mostile G, Padovani A, Pilotto A, Modugno N, Olivola E, Demartini B, Nisticò V, Erro R, Cuoco S, Tessitore A, De Micco R, Ceravolo R, Del Prete E, Dallocchio C, Arbasino C, Bono F, Mummolo C, Esposito M, Trinchillo A, Fabbrini G, Ferrazzano G, Petracca M, Piano C, Bonanni L, Carrarini C, Albanese A, Artusi CA, Defazio G, Caruso P, Calandra-Buonaura G, Morgante F, Pisani A, Solla P, Tinazzi M, Italian Registry of Functional Motor Disorders (IRFMD) study group.   +43 more
europepmc   +1 more source