Results 51 to 60 of about 925,078 (312)

Theories of developmental dyslexia: Insights from a multiple case study of dyslexic adults [PDF]

open access: yes, 2002
A multiple case study was conducted in order to assess three leading theories of developmental dyslexia: the phonological, the magnocellular (auditory and visual) and the cerebellar theories.
Castellote, Juan M.   +6 more
core   +3 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Neuropilin 1 sequestration by neuropathogenic mutant glycyl-tRNA synthetase is permissive to vascular homeostasis

open access: yesScientific Reports, 2017
The mechanism by which dominantly inherited mutations in the housekeeping gene GARS, which encodes glycyl-tRNA synthetase (GlyRS), mediate selective peripheral nerve toxicity resulting in Charcot-Marie-Tooth disease type 2D (CMT2D) is still largely ...
James N. Sleigh   +5 more
doaj   +1 more source

Methodological advances in imaging intravital axonal transport [version 1; referees: 3 approved]

open access: yesF1000Research, 2017
Axonal transport is the active process whereby neurons transport cargoes such as organelles and proteins anterogradely from the cell body to the axon terminal and retrogradely in the opposite direction.
James N. Sleigh   +3 more
doaj   +1 more source

In vivo assessment of neurodegeneration in Spinocerebellar Ataxia type 7

open access: yesNeuroImage: Clinical, 2021
Spinocerebellar Ataxia type 7 (SCA7) is a neurodegenerative disease characterized by progressive cerebellar ataxia and retinal degeneration. Increasing loss of visual function complicates the use of clinical scales to track the progression of motor ...
Jacob A. Parker   +9 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

The relationship between motor control and phonology in dyslexic children [PDF]

open access: yes, 2002
Background: The goal of this study was to investigate the automaticity/cerebellar theory of dyslexia. We tested phonological skills and cerebellar function in a group of dyslexic 8-12 year old children and their matched controls.
Frith, Uta   +2 more
core   +1 more source

The history of written language disorders: reexamining Pitres’ case (1884) of pure agraphia [PDF]

open access: yes, 2003
The first clinical description of pure agraphia was reported by the French neurologist Pitres in 1884. Pitres used the case study evidence to argue for modality-specific memory representations and the localization of writing.
Aimard   +66 more
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Hubungan Pemberian Asi Eksklusif, Jenis Kelamin Dan Status Gizi Terhadap Perkembangan Motorik Kasar Pada Anak Usia 3-5 Tahun Di Kelurahan Makam Haji [PDF]

open access: yes, 2018
The high rate of incidence of growth and developmental disorders in children aged under five in particular motor development disorders obtained (27.5%) or 3 million children have interference.
, Dr. Iwan Setiawan, Sp.S., M.Kes.   +1 more
core  

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