Results 71 to 80 of about 502,314 (315)
A Pilot Study of Botulinum Toxin for Jerky, Position-Specific, Upper Limb Action Tremor
Background: We aimed to investigate the efficacy and safety of botulinum toxin (BT) injections for jerky action tremor of the upper limb.Methods: We performed an uncontrolled, prospective study of electromyography (EMG)-guided BT injections for jerky ...
Tabish A. Saifee +4 more
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Art therapy and its influence on body image in women facing breast cancer
Introduction: Breast cancer has both physical and psychosocial consequences. Therefore, within holistic rehabilitation approaches, the implementation of various therapeutic programmes – including those integrating complementary and expressive art ...
Emilia Jug +3 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Longitudinal imaging in C9orf72 mutation carriers: Relationship to phenotype
Expansion mutations in the C9orf72 gene may cause amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), or mixtures of the two clinical phenotypes. Different imaging findings have been described for C9orf72-associated diseases in comparison
Mary Kay Floeter +5 more
doaj +1 more source
RESTORATION OF MOTOR AND NON-MOTOR FUNCTIONS BY NEUROTROPHIC FACTORS IN NONHUMAN PRIMATES WITH DOPAMINE DEPLETION [PDF]
Parkinson’s disease (PD) is a progressive debilitating neurodegenerative disorder characterized by resting tremor, rigidity, bradykinesia and postural instability. As the disease progresses there is a loss of dopamine (DA) neurons in the substantia nigra
Subramanian, Krishna
core
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Hypokinetic dysarthria is a common manifestation of Parkinson's disease, which negatively influences quality of life. Behavioral techniques that aim to improve speech intelligibility constitute the bulk of intervention strategies for this population, as ...
Kaitlin L. Lansford +3 more
doaj +1 more source
Functional Motor Disorders in pediatrics: clinical motor correlates and neuropsychiatric profiles
Background: Functional Motor Disorders (FMDs) in pediatric age represent an increasing challenge among acute movement manifestations, mostly for functional tic during the pandemic. The aim of our study was to distinguish possible specific clinical motor
Cardona F., Baglioni V., Conte G.
core

