Results 91 to 100 of about 502,314 (315)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
, 2013 Visual-motor skill is fundamental to human development and is an important component of psychological evaluations. the goal of the present study was to determine whether there is a correlation between visual-motor development, as measured by the Bender ...
Schoen, Teresa Helena [UNIFESP] +2 more
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Activity monitoring in patients with depression : A systematic review [PDF]
, 2013 Copyright © 2012 Elsevier B.V.
McKinstry, Brian +5 more
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FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
The Factors that Induce or Overcome Freezing of Gait in Parkinson’s Disease
Behavioural Neurology, 2008 Freezing of gait (FoG), a transient halt in walking, is a major mobility problem for patients with Parkinson’s disease (PD). This study examined the factors that induce FoG, and identified the cues and strategies that help overcome it through a postal ...
S. Rahman +3 more
doaj +1 more source
Oral motor and language development. [PDF]
, 2002 Manual gesture has been shown to be related to normal language development, in that early gesture users become early talkers. In addition, different groups of speech and language impaired individuals (left-hemisphere CVA patients with nonfluent dysphasia,
Alcock, K. J., Gordon, E.
core
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
Behavioural Neurology, 2012 Changes of cognitive function in PD have been extensively documented and defined as a ‘frontal’ type executive dysfunction. One of the main components of this executive dysfunction is the impairment of verbal fluency.
Ignacio Obeso +4 more
doaj +1 more source
Middle Ear Myoclonus: Two Informative Cases and a Systematic Discussion of Myogenic Tinnitus
Tremor and Other Hyperkinetic Movements, 2013 Background: The term middle ear myoclonus (MEM) has been invoked to explain symptoms of tinnitus presumably caused by the dysfunctional movement of either of the two muscles that insert in the middle ear: tensor tympani and stapedius.
Aviva Ellenstein +2 more
doaj +1 more source
Movement difficulties in children
, 2011 The development of adequate motor control and coordination is an important part of general development, allowing an infant to interact with and learn about the world around them and making possible so many everyday activities for children - at home, at ...
Barnett, Anna, Hill, Elisabeth L.
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