Results 101 to 110 of about 502,314 (315)
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
On the Nature of Fear of Falling in Parkinson’s Disease
Behavioural Neurology, 2011 In the elderly, fear of falling (FoF) can lead to activity restriction and affect quality of life (QoL). Our aim was to identify the characteristics of FoF in Parkinson's disease and assess its impact on QoL.
S. Rahman +3 more
doaj +1 more source
A qualitative and quantitative study of the nature of developmental coordination disorder [PDF]
, 2006 AIMS The aim was to examine the theoretical and clinical plausibility of subtypes of movement difficulty, and explore the impact subtypes and/or additional factors would have on motor development. BACKGROUND Developmental Coordination Disorder (
Green, Dido
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Computations of uncertainty mediate acute stress responses in humans
Nature Communications, 2016 Acute stress has broad physiological and behavioural consequences, yet the precise factors that generate stress responses are not known. Here, de Berker and colleagues demonstrate that acute stress responses dynamically track environmental uncertainty ...
Archy O. de Berker +6 more
doaj +1 more source
The development of oral motor control and language. [PDF]
, 2006 Motor control has long been associated with language skill, in deficits, both acquired and developmental, and in typical development. Most evidence comes from limb praxis however; the link between oral motor control and speech and language has been ...
Alcock, Katherine Jane
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, 2014 Aim of the study was to investigate whether children aged 7–9 year old with severe motor difficulties had a greater risk of additional difficulties in activities in daily living (ADL), academic skills, attention and social skills than children with ...
Schoemaker, M +6 more
core +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Treatment of Essential Tremor with Long-chain Alcohols: Still Experimental or Ready for Prime Time?
Tremor and Other Hyperkinetic Movements, 2014 Aim: To review current literature on long‐chain alcohols and their derivatives as novel pharmacotherapy for the treatment of essential tremor (ET). Background: Currently available and recommended pharmacotherapies for ET are often limited ...
Dietrich Haubenberger +3 more
doaj +1 more source
, 2010 Includes bibliographical references (leaves 105-115).The functional integrity of the vestibular system in children is not often tested. Due to the close relationship between the cochlea and the peripheral vestibular system, the function of the vestibular
Geldenhuys, Wilhelmien
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