Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies
Aging and Cancer, EarlyView.This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal +8 more
wiley +1 more source
Evoked potentials as biomarkers of hereditary spastic paraplegias: A case-control study.
PLoS ONE, 2021 IntroductionThe Hereditary Spastic Paraplegias (HSP) are a group of genetic diseases that lead to slow deterioration of locomotion. Clinical scales seem to have low sensitivity in detecting disease progression, making the search for additional biomarkers
Samanta Ferraresi Brighente +8 more
doaj +1 more source
EPSPs in rat neocortical neurons in vitro. I. Electrophysiological evidence for two distinct EPSPs [PDF]
, 1989 1. To investigate excitatory postsynaptic potentials (EPSPs), intracellular recordings were performed in layer II/III neurons of the rat medial frontal cortex.
Hablitz, John H., Sutor, Bernd
core +1 more source
Progressive Myoclonus Epilepsy: Distinctive MRI Changes in Cerebellar and Motor Networks
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Progressive myoclonus epilepsy (PME) is a rare generalized epilepsy syndrome with a well‐characterized genetic basis. The brain networks that are affected to give rise to the distinctive symptoms of PME are less well understood. Methods Eleven individuals with PME with a confirmed genetic diagnosis and 22 controls were studied.
Jillian M. Cameron +3 more
wiley +1 more source
Dataset combining EEG, eye-tracking, and high-speed video for ocular activity analysis across BCI paradigms [PDF]
In Brain-Computer Interface (BCI) research, the detailed study of blinks is crucial. They can be considered as noise, affecting the efficiency and accuracy of decoding users' cognitive states and intentions, or as potential features, providing valuable insights into users' behavior and interaction patterns.
arxiv +1 more source
Evoke: Evoking Critical Thinking Abilities in LLMs via Reviewer-Author Prompt Editing [PDF]
arXiv, 2023 Large language models (LLMs) have made impressive progress in natural language processing. These models rely on proper human instructions (or prompts) to generate suitable responses. However, the potential of LLMs are not fully harnessed by commonly-used prompting methods: many human-in-the-loop algorithms employ ad-hoc procedures for prompt selection;
arxiv
Хирургия позвоночника, 2019 Objective. To assess the information value of comparing the results of formalizing intraoperative changes in transcranial motor evoked potentials during surgical correction of spinal deformities of various etiologies. Material and Methods.
Marat S. Saifutdinov +4 more
doaj +1 more source
Steady-State movement related potentials for brain–computer interfacing [PDF]
, 2008 An approach for brain-computer interfacing (BCI) by analysis of steady-state movement related potentials (ssMRPs) produced during rhythmic finger movements is proposed in this paper. The neurological background of ssMRPs is briefly reviewed.
Miall, RC +3 more
core +3 more sources
FGF14 GAA Intronic Expansion in Unsolved Adult‐Onset Ataxia in the Care4Rare Canada Consortium
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Spinocerebellar ataxias (SCA) represent a clinically and genetically heterogeneous group of progressive neurodegenerative diseases with prominent cerebellar atrophy. Recently, a novel pathogenic repeat expansion in intron 1 of FGF14 was identified, causing adult‐onset SCA (SCA27B). We aimed to determine the proportion
Alexanne Cuillerier +20 more
wiley +1 more source
The pathobiology of psychomotor slowing in psychosis: altered cortical excitability and connectivity. [PDF]
Psychomotor slowing is a frequent symptom of schizophrenia. Short-interval intracortical inhibition assessed by transcranial magnetic stimulation demonstrated inhibitory dysfunction in schizophrenia.
Gehrig, Gwendolyn +6 more
core +1 more source