Results 101 to 110 of about 485,714 (300)

Tactile-STAR: A Novel Tactile STimulator And Recorder System for Evaluating and Improving Tactile Perception [PDF]

, 2018
Many neurological diseases impair the motor and somatosensory systems. While several different technologies are used in clinical practice to assess and improve motor functions, somatosensation is evaluated subjectively with qualitative clinical scales ...
BALLARDINI, GIULIA, Giorgio Carlini, Ilana Nisky, Maura Casadio, Psiche Giannoni, Robert A. Scheidt   +5 more
core   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Transcranial optogenetic mapping revealed longitudinal changes in motor maps of ipsi-lesional and contra-lesional cortex following mild traumatic brain injury [PDF]

, 2016
poster abstractAbstract: Victims of traumatic brain injury (TBI) suffer short- and long-term physical, cognitive, behavioral and emotional impairments that depend on the severity of the injury. Mechanical and cellular alterations in mild TBI can cause
Al-Juboori, Mohammed, Jin, Xiaoming, Moore, Allison, Nguyen, Tyler, Ping, Xingjie, Walerstein, Jakub   +5 more
core  

Mapping the cortical representation of the lumbar paravertebral muscles [PDF]

, 2007
Objective: The aim of this study was to map the cortical representation of the lumbar spine paravertebral (LP) muscles in healthy subjects. Methods: Transcranial magnetic stimulation (TMS) was employed to map the cortical representations of the LP ...
A.V. Nowicky, Arai, Cariga, D.W. Maskill, Eguchi, Ferbert, Fink, Flor, Gandevia, Godschalk, J. Cossar, Lariviere, Liepert, Maskill, McMillan, N.E. O’Connell, Nowicky, Nudo, Nudo, Nudo, Plassman, Rossini, Schmidlin, Schwenkreis, Sharshar, Sommer, Strutton, Toldi, Tunstill, Wasserman, Wilson, Zanette, Ziemann   +32 more
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Current status and potential application of navigated transcranial magnetic stimulation in neurosurgery: a literature review

Chinese Neurosurgical Journal, 2019
Transcranial magnetic stimulation (TMS) is a noninvasive neurophysiologic technique that can stimulate the human brain. Positioning of the coil was often performed based merely on external landmarks on the head, meaning that the anatomical target in the ...
Xiaojing Fang, Meige Liu, Changyu Lu, Yuanli Zhao, Xianzeng Liu   +4 more
doaj   +1 more source

An Electrocorticographic Brain Interface in an Individual with Tetraplegia [PDF]

, 2013
Brain-computer interface (BCI) technology aims to help individuals with disability to control assistive devices and reanimate paralyzed limbs. Our study investigated the feasibility of an electrocorticography (ECoG)-based BCI system in an individual with
Ashmore, RC, Boninger, ML, Collinger, JL, Degenhart, AD, Kelly, JW, Moran, DW, Schwartz, AB, Tyler-Kabara, EC, Vinjamuri, RK, Wang, W, Weber, DJ, Wodlinger, B   +11 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Unsupervised decoding of long-term, naturalistic human neural recordings with automated video and audio annotations [PDF]

, 2015
Fully automated decoding of human activities and intentions from direct neural recordings is a tantalizing challenge in brain-computer interfacing.
Brunton, Bingni W., Ojemann, Jeffrey G., Olson, Jared D., Rao, Rajesh P. N., Wang, Nancy X. R.   +4 more
core   +3 more sources

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source