Results 161 to 170 of about 305,411 (311)

Investigation of the interaction between corticomuscular coherence, motor precision and perceived difficulty in wrist flexion and extension

, 2013
Includes abstract.Includes bibliographical references.Recently, behavioural (motor precision) differences were reported between isometric wrist flexion and extension.
Divekar, Nikhil Vishwas
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

The association between motor coordination impairment and altered functional connectivity among autistic children

Frontiers in Pediatrics
BackgroundMotor coordination impairment among children with autism spectrum disorder (ASD) has recently gained increasing attention. However, the relationship between functional connectivity (FC) alterations and motor coordination impairment among ASD ...
Muqing Cao, Chengkai Jin, Jin Jing
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Abnormal EEG Spectral Power and Coherence Measures During Pre-Motor Stage in Amyotrophic Lateral Sclerosis

IEEE Transactions on Neural Systems and Rehabilitation Engineering
Amyotrophic lateral sclerosis (ALS) is a multisystem neurodegenerative disorder characterized by progressive motor decline. Studies of electroencephalographic (EEG) activity during rest and motor execution have captured network changes in ALS.
Saroj Bista, Amina Coffey, Matthew Mitchell, Antonio Fasano, Stefan Dukic, Teresa Buxo, Eileen Giglia, Mark Heverin, Muthuraman Muthuraman, Richard G. Carson, Madeleine Lowery, Lara McManus, Orla Hardiman, Bahman Nasseroleslami   +13 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Optimized connectome architecture for sensory-motor integration

, 2017
This record is for a(n) offprint of an article published in Network Neuroscience on 2017-12-31; the version of record is available at https://doi.org/10.1162/netn_a_00022.The intricate connectivity patterns of neural circuits support a wide repertoire of
Mis_ic, Bratislav, Worrell, Jacob C., Rumschlag, Jeffrey, Sporns, Olaf, Betzel, Richard F.   +4 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Pengaturan Kecepatan Motor DC Menggunakan Jaringan Syaraf Tiruan Feedforward Backpropagation [PDF]

, 2011
Jaringan syaraf backpropagation merupakan jaringan syaraf yang telah umum digunakan dalam beragam aplikasi kontrol. Dari segi arsitektur, backpropagation merupakan jaringan syaraf perceptron dengan banyak layer (multilayer), sehingga jaringan syaraf
Wahyudi , Wahyudi, Sorikhi, Sorikhi, Setiawan, Iwan   +2 more
core  

Alterations in beta oscillatory activity occur with the emergence of parkinsonian motor signs across the basal ganglia-thalamocortical network

Neurobiology of Disease
Mounting evidence suggests that elevated beta oscillatory activity in the basal ganglia thalamocortical (BGTC) network is associated with the cardinal motor signs in people with Parkinson's disease (PD).
Eesha Bharti, Adele L. DeNicola, Ying Yu, Ajay K. Verma, David Schneck, Biswaranjan Mohanty, Mark Fiecas, Hongyu Yao, Jing Wang, Luke A. Johnson, Jerrold L. Vitek   +10 more
doaj   +1 more source