Results 121 to 130 of about 423,991 (315)

肌萎缩侧索硬化医疗质量控制指标 Medical Quality Control Indicators for Amyotrophic Lateral Sclerosis

open access: yesZhongguo cuzhong zazhi
国家神经系统疾病医疗质量控制中心于2022年设立了运动神经元病(motor neuron disease,MND)质控专病组,启动了肌萎缩侧索硬化(amyotrophic lateral sclerosis,ALS)/MND医疗质量控制体系建设。通过系统调研循证医学证据和国内外指南,MND质控专病组利用德尔菲法制定了ALS医疗质量控制指标体系,从统一诊断标准,建立患者全面管理概念,规范治疗方案等方面系统完善ALS的住院诊疗质量控制过程。该ALS医疗质量控制指标体系共15个指标 ...
The Motor Neuron Disease Working Group of National Center for Healthcare Quality Management in Neurological Diseases
doaj   +1 more source

Exploring Nasal Structural‐Microbial Interactions in Multiple Sclerosis‐Associated Olfactory Impairment

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Olfactory dysfunction is frequently observed in patients with multiple sclerosis (MS); however, its underlying mechanisms remain poorly understood. To date, no studies have directly examined the nasal mucosal microbiota in MS. This study aimed to explore potential relationships among olfactory function, nasal microbiota composition,
Zidan Gao   +5 more
wiley   +1 more source

CSF Mitochondrial DNA: Biomarker of Body Composition and Energy Metabolism in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebrospinal fluid (CSF) cell‐free mitochondrial DNA (cf‐mtDNA) is a potential biomarker for Parkinson's disease (PD), but its clinical relevance remains unclear. We investigated associations between CSF cf‐mtDNA levels, body composition, nutritional status, and metabolic biomarkers in PD. Methods CSF cf‐mtDNA levels, defined as the
Yasuaki Mizutani   +11 more
wiley   +1 more source

Nerve Excitability in Asymptomatic Carriers and Amyotrophic Lateral Sclerosis Patients With C9orf72

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We investigated the effects of C9orf72 mutation carriership on peripheral nerve excitability in asymptomatic individuals from families with a history of C9orf72 amyotrophic lateral sclerosis (ALS) and patients. Methods We included 47 asymptomatic individuals from families with a history of C9orf72 ALS, of whom 23 were carriers (C9 ...
Diederik J. L. Stikvoort García   +3 more
wiley   +1 more source

Retrovirus-induced murine motor neuron disease: mapping the determinant of spongiform degeneration within the envelope gene.

open access: green, 1989
Yves Paquette   +5 more
openalex   +1 more source

Moyamoya Disease and the Risk of Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Moyamoya disease (MMD) is a rare cerebrovascular disorder characterized by the progressive narrowing of arteries at the base of the brain, forming abnormal collateral vascular networks. While vascular parkinsonism is noted in MMD, its link to Parkinson's disease (PD) has not been explored.
Dallah Yoo   +9 more
wiley   +1 more source

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