Results 191 to 200 of about 247,506 (355)

Engineering Topographical Cues to Enhance Neural Regeneration in Spinal Cord Injury: Overcoming Challenges and Advancing Therapies

Advanced Functional Materials, EarlyView.
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu, Fenghui Wang, Joshua Stein, Siqiao Wang, Pengfei Jiang, Letao Yang, Liming Cheng, Ki‐Bum Lee   +7 more
wiley   +1 more source

Dose-dependent CHCHD10 dysregulation dictates motor neuron disease severity and alters creatine metabolism. [PDF]

Acta Neuropathol Commun
Harjuhaahto S, Jokela M, Rajendran J, Rokka M, Hu B, Kvist J, Zhang F, Zárybnický T, Haimilahti K, Euro L, Pirinen E, Huber N, Herukka SK, Haapasalo A, Kuuluvainen E, Gopalakrishnan S, Katajisto P, Hietakangas V, Burg T, Van Den Bosch L, Huang X, Narendra DP, Kuure S, Ylikallio E, Tyynismaa H.   +24 more
europepmc   +1 more source

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

, 1995
Philip C. Wong, Carlos A. Pardo, David Borchelt, Michael K. Lee, Neal G. Copeland, Nancy A. Jenkins, Sangram S. Sisodia, Don W. Cleveland, Donald L. Price   +8 more
openalex   +1 more source

Dimer destabilization in superoxide dismutase may result in disease-causing properties: Structures of motor neuron disease mutants [PDF]

, 2004
Michael A. Hough, J. Günter Grossmann, S.V. Antonyuk, Richard W. Strange, Peter A. Doucette, Jorge Rodríguez, Lisa J. Whitson, P. John Hart, Lawrence J. Hayward, Joan Selverstone Valentine, S.S. Hasnain   +10 more
openalex   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

An Evaluation of the United Kingdom Motor Neuron Disease Nurses and Allied Health Professionals (UK MND NAHP) Workforce: A Census. [PDF]

PLoS One
Chau I, Stoker E, Gill J, Newton J, United Kingdom Motor Neuron Disease Nurses and Allied Health Professionals Consortium.   +4 more
europepmc   +1 more source

Restoration of aspartoacylase activity in CNS neurons does not ameliorate motor deficits and demyelination in a model of Canavan disease [PDF]

, 2005
Matthias Klugmann, Claudia B. Leichtlein, C. Wymond Symes, Tadao Serikawa, Deborah Young, Matthew J. During   +5 more
openalex   +1 more source

Label‐Free and Low‐Power Driven Cancer Biomarker Detection Enabled by 2D Hexagonal Titanium Oxide

Advanced Functional Materials, EarlyView.
A low‐power driven FET biosensor based on 2D hexagonal TiO2 detects the cancer biomarker carcinoembryonic antigen with high sensitivity, a low detection limit of 0.22 pg mL−1, and excellent selectivity. Leveraging the unique electronic properties of the material, this work demonstrates strong potential for integration into miniature and portable cancer
Yange Luan, Qijie Ma, Yihong Hu, Xinyi Hu, Guanyu Chen, Jiaru Zhang, Zhong Li, Dongdong Xie, Guanghui Ren, Yunyi Yang, Guifu Ding, Kate Fox, Bao Yue Zhang, Jian Zhen Ou   +13 more
wiley   +1 more source

Peripheral Nerve Lesions in a Case of Equine Motor Neuron Disease.

, 1999
Hidefumi Furuoka, Mituru Hasegawa, Yoshiyasu KOBAYASHI, T. Matsui   +3 more
openalex   +2 more sources

THEME 5 Improving Diagnosis and Prognosis in Motor Neuron Diseases [PDF]

, 2005

openalex   +1 more source