Results 211 to 220 of about 293,569 (356)

Synaptic and cytoskeletal CSF signatures of motor neuron disease: the role of cyclase-associated protein 2. [PDF]

open access: yesSci Rep
Pilotto A   +14 more
europepmc   +1 more source

Process evaluation and exploration of telehealth in motor neuron disease in a UK specialist centre [PDF]

open access: gold, 2019
Esther Hobson   +8 more
openalex   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao   +7 more
wiley   +1 more source

Efficient induction of motor neuron disease in transgenic G93A SOD1 mice by prion-like seeding. [PDF]

open access: yesPrion
Xu G   +5 more
europepmc   +1 more source

Retrograde axonal transport and motor neuron disease [PDF]

open access: bronze, 2008
Anna‐Lena Ström   +5 more
openalex   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi   +8 more
wiley   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

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