Results 111 to 120 of about 1,687,398 (262)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Performance of a UTC FW-4S solid propellant rocket motor under the command effects of simulated altitude and rotational spin [PDF]

open access: yes
One United Technology Center FW-4S solid-propellant rocket motor was fired at an average simulated altitude of 103,000 ft while spinning about its axial centerline at 180 rpm. The objectives of the test program were to determine motor altitude ballistic
Merryman, H. L., Smith, L. R.
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Torque control of switched reluctance motors [PDF]

open access: yes, 2011
This paper presents the performance of an instantaneous torque control method. The simulation and experimental results illustrate the capability of Switched Reluctance Motors (SRM) being used in the motor drive industry. Based on experimental data, the
García García, Alfonso   +3 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Motor control of a hub motor for electric skateboard propulsion : a thesis presented in partial fulfilment of the requirements for the degree of Masters in Engineering at Massey University, Palmerston North, New Zealand [PDF]

open access: yes, 2016
Redacted for copyright reasons: Appendix A - Journal Article Published in IEEE International Instrumentation and Measurement Technology Conference (I2MTC 2012). Rowe, A. & Sen Gupta, G. (2012).
Rowe, Alex
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Limits of feedback control in bacterial chemotaxis

open access: yes, 2014
Inputs to signaling pathways can have complex statistics that depend on the environment and on the behavioral response to previous stimuli. Such behavioral feedback is particularly important in navigation.
Dufour, Yann S.   +3 more
core   +3 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Optimal Schedules in Multitask Motor Learning [PDF]

open access: yes, 2016
Although scheduling multiple tasks in motor learning to maximize long-term retention of performance is of great practical importance in sports training and motor rehabilitation after brain injury, it is unclear how to do so.
Kim, Sung Shin   +4 more
core   +1 more source

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