Results 101 to 110 of about 446,718 (283)
FEBS Letters, EarlyView.PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley +1 more source
Developing physical activity interventions for children with a visual impairment:lessons from the First Steps initiative [PDF]
, 2019 Children with a visual impairment are less active than their sighted peers. Yet they are born with the potential to match their sighted peers’ motor skill competency and levels of physical fitness.
Lord, Rhiannon, Scally, Jennifer
core +2 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Does stereopsis account for the link between motor and social skills in adults?
Molecular Autism, 2018 Background Experimental and longitudinal evidence suggests that motor proficiency plays an important role in the development of social skills. However, stereopsis, or depth perception, may also play a fundamental role in social skill development either ...
Danielle Smith +2 more
doaj +1 more source
Effects of Force Level and Hand Dominance on Bilateral Transfer of a Fine Motor Skill [PDF]
, 2016 Our research is about bilateral transfer, a concept in motor learning where skills learned by one limb are "transferred", allowing the opposite limb to benefit from what was learned by the first limb.
Muller, Karl, Rai, Aakarsh
core +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
The effect of traditional games in fundamental motor skill development in 7-9 year old boys [PDF]
Objective: The purpose of this study was to investigate the effect of traditional games on fundamental motor skills in seven to nine year-old boys.
Abdoli, Behroz +5 more
core
Context-dependent motor skill and the role of practice [PDF]
, 2011 Research has shown that retrieval of learned information is better when the original learning context is reinstated during testing than when this context is changed.
Abrahamse, E.L. +4 more
core +3 more sources
Is body fat mass associated with worse gross motor skills in preschoolers? An exploratory study
, 2022 Juliana Nogueira Pontes Nobre +9 more
openalex +1 more source