Results 121 to 130 of about 446,718 (283)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Changes in spinal motoneuron excitability during the improvement of fingertip dexterity by actual execution combined with motor imagery practice

Heliyon
Since there is an upper limit to skill improvement through the repetition of actual execution, we examined whether motor imagery could be used in combination with actual execution to maximize motor skill improvement.
Yuki Fukumoto, Marina Todo, Makoto Suzuki, Daisuke Kimura, Toshiaki Suzuki   +4 more
doaj   +1 more source

Score of Fine Motor Skill in Children with Down Syndrome using Nintendo Wii

Althea Medical Journal, 2016
Background: Down syndrome occurs due to an extra chromosome 21, known as Trisomy 21. In addition to delayed cognitive and speech development, children with Down syndrome may also experience delayed gross and fine motor development.
Puspasari Sinaga, Marietta Shanti Prananta, Eddy Fadlyana   +2 more
doaj   +1 more source

Property as Constitutional Myth: Utilities and Dangers [PDF]

, 2003
The ability to perform everyday life occupations is a critical component in both evaluation and intervention for persons with mental retardation (MR). While the ability to perform personal and instrumental activities of daily living (ADL) has always been
Underkuffler, Laura S.
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Increased perceptions of autonomy through choice over one's observation schedule fail to enhance motor skill retention

, 2021
Laura St. Germain, Allison Williams, Noura Balbaa, Andrew Poskus, Olena Leshchyshen, Keith R. Lohse, Michael J Carter   +6 more
openalex   +1 more source

Nigella sativa Oil Improves Motor Skill Learning of Albino Mice: In Vivo and In Silico Investigations [PDF]

, 2023
Md. Siam Hossain, Abu Baker Seddique, Sharmin Suraiya, Md. Mamun Or Rashid, Arifin Islam, Md. Monir Hossain   +5 more
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Comparison of Fine Motor Skills in Patients With Chronic Stroke in Final Stages of Bronestrum and Healthy Adults [PDF]

, 2015
Mina Sadat Mirshoja, Ali Akbar Pahlevanian, Mohammad Amoozadeh Khalili   +2 more
openalex   +1 more source

EFFECTIVENESS OF GIANT EDUCATIONAL GAME MEDIA FOR IMPROVEMENT MOTOR SKILLS

, 2022
Dewi Indah Noviana Pratiwi, Setiawan Budi Santoso, F.R. Vafazov, Moh Kanzunnudin, Gulzhaina K. Kassymova   +4 more
openalex   +1 more source