Results 221 to 230 of about 3,573,680 (398)

Motor skill learning requires active central myelination

open access: yesScience, 2014
I. Mckenzie   +6 more
semanticscholar   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

An Eight-Week Physical Activity Intervention is Associated With Gross Motor Skills in Preschool Children

open access: green, 2018
Azeem A Hussain   +6 more
openalex   +1 more source

Fundamental Motor Skills Mediate the Relationship Between Physical Fitness and Soccer-Specific Motor Skills in Young Soccer Players

open access: gold, 2019
Jakub Kokštejn   +4 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Fine motor skill training enhances functional plasticity of the corticospinal tract after spinal cord injury

open access: gold, 2016
Xiaoyu Yang   +5 more
openalex   +1 more source

Home - About - Disclaimer - Privacy