Results 301 to 310 of about 3,573,680 (398)

Relationship Between Within-Session Digital Motor Skill Acquisition and Alzheimer Disease Risk Factors Among the MindCrowd Cohort: Cross-Sectional Descriptive Study. [PDF]

JMIR Aging
Hooyman A, Huentelman MJ, De Both M, Ryan L, Duff K, Schaefer SY.   +5 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Neural plasticity in early potters: Shape analysis and TMS-EEG co-registration trace the rise of a new motor skill. [PDF]

PLoS One
Forte V, Sartori L, Visalli A, Yildirim M, Galati G, Vidale M, Faresin E, Vallesi A.   +7 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

The Relationship Between Obesity Status and Body Image Dissatisfaction on Gross Motor Skill Development and Cardiorespiratory Fitness in Children Aged 6-12 Years Old. [PDF]

Int J Environ Res Public Health
Allisse M, Thibault I, Gagnon D, Kalinova E, Larivière G, Leone M.   +5 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

The Correlation between Motor Skill Proficiency and Academic Performance in High School Students. [PDF]

Behav Sci (Basel)
Ramos-Campo DJ, Clemente-Suárez VJ.
europepmc   +1 more source

Exploring Functional Networks of the Brain Relating to Upper Extremity Motor Skill Using Graph Theory [PDF]

, 2012
Guastello, Stephen, Jeutter, Dean C, Nathan, Dominic, Prost, Robert W   +3 more
core   +1 more source

The effect of skill exercises combined with audiovisual stimulation in developing motor response speed and performance of some basic defensive skills for young soccer goalkeepers

Muhammad Sh Hamid, Furat J Saadulla
openalex   +2 more sources

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source