Results 81 to 90 of about 446,718 (283)
Vocal learning promotes patterned inhibitory connectivity. [PDF]
, 2017 Skill learning is instantiated by changes to functional connectivity within premotor circuits, but whether the specificity of learning depends on structured changes to inhibitory circuitry remains unclear.
Brainard, Michael S +2 more
core +2 more sources
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
An introduction to the constraints-led approach to learning in outdoor education [PDF]
, 2010 Participation in outdoor education is underpinned by a learner's ability to acquire skills in activities such as canoeing, bushwalking and skiing and consequently the outdoor leader is often required to facilitate skill acquisition and motor learning. As
Brymer, Eric, Renshaw, Ian
core +1 more source
Damage to fronto-parietal networks impairs motor imagery ability after stroke : a voxel-based lesion symptom mapping study [PDF]
, 2016 Background: mental practice with motor imagery has been shown to promote motor skill acquisition in healthy subjects and patients. Although lesions of the common motor imagery and motor execution neural network are expected to impair motor imagery ...
Oostra, Kristine M +3 more
core +2 more sources
The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells
FEBS Letters, EarlyView.The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman +3 more
wiley +1 more source
Learning Redundant Motor Tasks With and Without Overlapping Dimensions: Facilitation and Interference Effects [PDF]
, 2014 Prior learning of a motor skill creates motor memories that can facilitate or interfere with learning of new, but related, motor skills. One hypothesis of motor learning posits that for a sensorimotor task with redundant degrees of freedom, the nervous ...
Mosier, Kristine M. +4 more
core +2 more sources
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
Neural substrates underlying motor skill learning in chronic hemiparetic stroke patients
Frontiers in Human Neuroscience, 2015 Motor skill learning is critical in post-stroke motor recovery, but little is known about its underlying neural substrates. Recently, using a new visuomotor skill learning paradigm involving a speed/accuracy trade-off in healthy individuals we identified
Stephanie eLefebvre +13 more
doaj +1 more source
Journal of NeuroEngineering and Rehabilitation, 2020 Background Virtual reality viewed using a head-mounted display (HMD-VR) has the potential to be a useful tool for motor learning and rehabilitation.
Julia M. Juliano, Sook-Lei Liew
doaj +1 more source
Motor skill learning depends on protein synthesis in the dorsal striatum after training [PDF]
, 2018 Functional imaging studies in humans and electrophysiological data in animals suggest that corticostriatal circuits undergo plastic modifications during motor skill learning.
Frank, Anita +7 more
core