Results 211 to 220 of about 3,177,616 (255)

Editorial: Cognitive and motor skills in sports. [PDF]

Front Psychol
Schaefer S, Zentgraf K, Steel KA.
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Effects of Exergame-Based Interventions on Executive Functions and Motor Skills in Children with Autism Spectrum Disorder: A Systematic Review. [PDF]

Sports (Basel)
Vigil-Torres N, Carcelén-Fraile MDC, Martínez-Redecillas T, Cecic-Mladinic D.   +3 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Enhancing Parent-Child Interaction and Self-Efficacy in Motor Skills Development for Young Children with Developmental Delays. [PDF]

Children (Basel)
Lai YL, Chu SY, Lee IH, Yang HW.
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Validation of FUNMOVES: A reliable tool for assessing motor skills in Spanish schoolchildren. [PDF]

PLoS One
Lizoain P, Romero DR, Reyes-Vivanco C, Preston N, Eddy LH, Hill LJB, Magallón S, Martínez M.   +7 more
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Effects of Developmental Gymnastics Exercise Program on Preschoolers' Motor Skills: A Randomised Controlled Trial. [PDF]

Children (Basel)
Radanović D, Marinković D, Mačak D, Milić Z, Popović B, Pantović M, Madić DM.   +6 more
europepmc   +1 more source