Results 31 to 40 of about 528,116 (352)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Motor vehicle inspection and motor vehicle accident mortality. [PDF]

open access: yesAmerican Journal of Public Health and the Nations Health, 1968
THIS STUDY SOUGHT TO DISCOVER IF STATES WITH COMPULSORY MOTOR VEHICLE INSPECTION EXHIBIT LOWER MOTOR VEHICLE MORTALITY RATES. THE YEAR 1960 WAS CHOSEN FOR THE STUDY BECAUSE OF THE COMPLETENESS OF THE INFORMATION AVAILABLE FROM THE CENSUS. IN THAT YEAR, 17 STATES, INCLUDING THE DISTRICT OF COLUMBIA, HAD COMPULSORY MOTOR VEHICLE INSPECTION.
T, Colton, R C, Buxbaum
openaire   +2 more sources

In-wheel axial-flux SRM drive for light electric vehicles [PDF]

open access: yes, 2018
Revenues from global sales of light electric vehicles are expected to grow from $ 9.3 billion in 2017 to $ 23.9 billion in 2025. In order to boost this growth electric drives with better features and lower costs have to be developed.
Andrada Gascón, Pedro   +5 more
core  

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

The Influence of Laser Alloying with Boron on the Condition and Properties of the Surface Layer of Selected Iron Alloys

open access: yesLubricants
This article presents the effect of laser alloying with boron on the surface layer of iron alloys: steel and grey cast iron. The general goal of this review is to specify the main differences that can be expected after this treatment of selected iron ...
Marta Paczkowska
doaj   +1 more source

Determination of Combustion Process Model Parameters in Diesel Engine with Variable Compression Ratio

open access: yesJournal of Combustion, 2018
Compression ratio has very important influence on fuel economy, emission, and other performances of internal combustion engines. Application of variable compression ratio in diesel engines has a number of benefits, such as limiting maximal in cylinder ...
Saša Milojević, Radivoje Pešić
doaj   +1 more source

Analysis and Recommendations for the Property Tax on Motor Vehicles in Georgia - Brief [PDF]

open access: yes, 2007
This report discusses the economic effects, including revenue effects, of eliminating or reducing the state property tax in motor vehicles.
Laura Wheeler
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Modification of the Surface Layer of Grey Cast Iron by Laser Heat Treatment

open access: yesLubricants
This paper presents possible modifications to the properties of grey cast iron by laser heat treatment. These modifications are analyzed especially with regard to wear properties as a result of graphite content, which is a well-known solid lubricant ...
Marta Paczkowska
doaj   +1 more source

Analysis and Recommendations for the Property Tax on Motor Vehicles in Georgia [PDF]

open access: yes, 2007
This report discusses the economic effects, including revenue effects, of eliminating or reducing the state property tax in motor vehicles.
Laura Wheeler
core  

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