Results 51 to 60 of about 4,734,862 (351)

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Efficiency assessment of different highspeed tracked vehicle hybrid powertrain conceptions

Vojnotehnički Glasnik
Introduction/purpose: Increased development of hybrid powertrains during the last decade brought high-speed tracked vehicles into the same spotlight as commercial and passenger hybrid vehicles.
Luka M. Ponorac, Ivan A. Blagojević
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Fuel Cell Electric Vehicles—A Brief Review of Current Topologies and Energy Management Strategies

Energies, 2021
With the development of technologies in recent decades and the imposition of international standards to reduce greenhouse gas emissions, car manufacturers have turned their attention to new technologies related to electric/hybrid vehicles and electric ...
I. Sorlei, N. Bizon, P. Thounthong, M. Varlam, Elena Carcadea, M. Culcer, M. Iliescu, Mircea Raceanu   +7 more
semanticscholar   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

83rd Legislature of Texas

, 2012
Report submitted by the Texas Department of Motor Vehicles containing background information on the department, and summaries of requests for appropriations and expenditures for the fiscal years 2014 and 2015 with supporting ...
Texas. Department of Motor Vehicles.
core   +1 more source

R455A Refrigerant as a Prospective Working Fluid in Refrigeration Systems for Gastronomy Furnishings

Energies
The general development of technology and universal access means that gastronomy furnishings can be found in every corner of the world. Therefore, it is important to develop these devices and the machines that constitute them.
Tomasz Bernat, Krzysztof Bieńczak
doaj   +1 more source

Numerical Investigation of Injection Timing Influence on Fuel Slip and Influence of Compression Ratio on Knock Occurrence in Conventional Dual Fuel Engine

Journal of Sustainable Development of Energy, Water and Environment Systems, 2017
Compressed natural gas can be used in diesel engine with great benefits, but because of its low reactivity it is usually used in a so called dual fuel combustion process.
Mario Sremec, Ivan Taritaš, Momir Sjerić, Darko Kozarac   +3 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Methodology of Multiple-Criteria Decision Making for Selecting a Refrigerant to Be Used in Commercial Refrigeration Equipment

Energies
This paper presents the application of the multiple-criteria decision-making (SAW) method for selecting the optimum refrigerant for the refrigeration systems of commercial cooling equipment used in gastronomy furniture, which is paramount in storing food
Tomasz Bernat, Krzysztof Bieńczak
doaj   +1 more source