Results 31 to 40 of about 1,719,006 (255)

Efficiency assessment of different highspeed tracked vehicle hybrid powertrain conceptions

Vojnotehnički Glasnik
Introduction/purpose: Increased development of hybrid powertrains during the last decade brought high-speed tracked vehicles into the same spotlight as commercial and passenger hybrid vehicles.
Luka M. Ponorac, Ivan A. Blagojević
doaj   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

83rd Legislature of Texas

, 2012
Report submitted by the Texas Department of Motor Vehicles containing background information on the department, and summaries of requests for appropriations and expenditures for the fiscal years 2014 and 2015 with supporting ...
Texas. Department of Motor Vehicles.
core   +1 more source

Motorcycle operator manual. [PDF]

, 2011
[Rev. 01-11].; Title from cover.; "Prepared by Motorcycle Safety Foundation. Adapted with Permission by Connecticut Department of Motor Vehicles"--1st prelim.

core   +1 more source

R455A Refrigerant as a Prospective Working Fluid in Refrigeration Systems for Gastronomy Furnishings

Energies
The general development of technology and universal access means that gastronomy furnishings can be found in every corner of the world. Therefore, it is important to develop these devices and the machines that constitute them.
Tomasz Bernat, Krzysztof Bieńczak
doaj   +1 more source

Numerical Investigation of Injection Timing Influence on Fuel Slip and Influence of Compression Ratio on Knock Occurrence in Conventional Dual Fuel Engine

Journal of Sustainable Development of Energy, Water and Environment Systems, 2017
Compressed natural gas can be used in diesel engine with great benefits, but because of its low reactivity it is usually used in a so called dual fuel combustion process.
Mario Sremec, Ivan Taritaš, Momir Sjerić, Darko Kozarac   +3 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Methodology of Multiple-Criteria Decision Making for Selecting a Refrigerant to Be Used in Commercial Refrigeration Equipment

Energies
This paper presents the application of the multiple-criteria decision-making (SAW) method for selecting the optimum refrigerant for the refrigeration systems of commercial cooling equipment used in gastronomy furniture, which is paramount in storing food
Tomasz Bernat, Krzysztof Bieńczak
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source