Results 51 to 60 of about 528,116 (352)
R455A Refrigerant as a Prospective Working Fluid in Refrigeration Systems for Gastronomy Furnishings
EnergiesThe general development of technology and universal access means that gastronomy furnishings can be found in every corner of the world. Therefore, it is important to develop these devices and the machines that constitute them.
Tomasz Bernat, Krzysztof Bieńczak
doaj +1 more source
Journal of Sustainable Development of Energy, Water and Environment Systems, 2017 Compressed natural gas can be used in diesel engine with great benefits, but because of its low reactivity it is usually used in a so called dual fuel combustion process.
Mario Sremec +3 more
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Quality Tests of Hybrid Joint–Clinching and Adhesive—Case Study
Applied Sciences, 2022 Inseparable joints are widely used in machine and vehicle construction. Hybrid joints include bonding with sheet metal clinching. This combination reduces costs as well as the time of production compared to welded joints.
Jakub Kowalczyk +5 more
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Value of Stolen Property Reported in Alaska, 1985–2016 [PDF]
, 2018 Data is available in both Excel and PDF format. (Download below.)This fact sheet presents data on the value of stolen property reported in Alaska from 1985 to 2016 as reported in the Department of Public Safety publication Crime in Alaska.
Reamey, Random
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Modelling the Ultrasonic Diagnosis of Adhesive Bonds
Communications, 2007 In the paper, the conception of modelling the diagnosis of adhesive bonds by ultrasonic method is presented. Two complementary models of bonds diagnosis are presented and discussed.
Marian Josko
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, 2022 This newsletter by the South Carolina Department of Motor Vehicles provides information for motor carrier customers, from commercial driver's licenses to International Registration Plan and International Fuel Tax Agreement ...
South Carolina Department of Motor Vehicles
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ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source