Results 41 to 50 of about 7,124,826 (230)

Relationship between motoric cognitive risk syndrome, cardiovascular risk factors and diseases, and incident cognitive impairment: Results from the “NuAge” study

, 2020
Motoric Cognitive Risk syndrome (MCR), which combines Subjective Cognitive Complaint (SCC) and slow gait speed in individuals free of dementia and gait disability, is associated with cardiovascular risk factors and diseases as well as incident cognitive ...
Beauchet, O., Launay, Cyrille P, Beauchet, Olivier, Gaudreau, Pierrette, Morais, José A., Sekhon, H., Sekhon, Harmehr, Allali, Gilles, Launay, C.P., Gaudreau, P., Morais, J.A., Allali, G.   +11 more
core   +1 more source

Motoric cognitive risk syndrome, incident cognitive impairment and morphological brain abnormalities: Systematic review and meta-analysis

, 2019
Motoric cognitive risk syndrome (MCR) is a pre-dementia stage, which associates slow walking speed with subjective cognitive impairment (SCI). MCR's clinical utility for the prediction of dementia and its pathophysiology are unclear.
Launay, Cyrille P, Wong, Chek Hooi, Beauchet, Olivier, Liu-Ambrose, T., Sekhon, H., Sekhon, Harmehr, Wong, C.H., Szturm, Tony, Liu-Ambrose, Teresa, Beauchet, O., Chester, V.L., Allali, Gilles, Barden, John, Launay, C.P., Szturm, T., Chester, Victoria L, Barden, J., Allali, G.   +17 more
core   +1 more source

Research progress on motoric cognitive risk syndrome in elderly

Huli yanjiu, 2021
To review the related concepts of motoric cognitive risk syndrome（MCR），the pathological mechanism of MCR，the epidemiological status of MCR in elderly，the influencing factors of MCR in elderly and the preventive warning effect of MCR on adverse health ...
JIN Congcong
doaj  

Do cognitive performance and physical function differ between individuals with motoric cognitive risk syndrome and those with mild cognitive impairment?

BMC Geriatrics, 2021
Background Motoric cognitive risk syndrome (MCR) is defined by slow gait speed combined with subjective cognitive complaint. MCR is a predementia syndrome, similar to mild cognitive impairment (MCI).
Fang-Yu Cheng, Yuanmay Chang, Shih-Jung Cheng, Jin-Siang Shaw, Chuo-Yu Lee, Pei-Hao Chen   +5 more
doaj   +1 more source

Motoric cognitive risk syndrome and incident dementia in older adults from the Québec NuAge cohort

, 2021
Background: The co-occurrence of slow walking speed and subjective cognitive complaint (SCC) in non-demented individuals defines motoric cognitive risk syndrome (MCR), which is a pre-dementia stage.
Launay, Cyrille P, Beauchet, Olivier, Sekhon, H., Sekhon, Harmehr, Cooper-Brown, L., Morais, José A, Beauchet, O., Cooper-Brown, Liam, Gaudreau, Pierrette, Allali, Gilles, Launay, C.P., Gaudreau, P., Morais, J.A., Allali, G.   +13 more
core   +1 more source

Risk factors, neuroimaging correlates and prognosis of the motoric cognitive risk syndrome: A population‐based comparison with mild cognitive impairment [PDF]

, 2022
BACKGROUND AND PURPOSE: This study was undertaken to compare risk factors, neuroimaging characteristics and prognosis between two clinical prodromes of dementia, namely, the motoric cognitive risk syndrome (MCRS) and mild cognitive impairment (MCI ...
Sirwan K. L. Darweesh, W. Vernooij, Meike, Mohammad Arfan Ikram, J. Wolters, Frank, Mohammad Kamran Ikram, Kamran Ikram, Mohammad, Yaqub, Amber; id_orcid, Darweesh, Sirwan K. L., Vernooij, Meike W., K. L. Darweesh, Sirwan, Arfan Ikram, Mohammad, Lisanne J. Dommershuijsen, Amber Yaqub, J. Wolters, Frank; id_orcid, Wolters, Frank J., Ikram, Mohammad Arfan, W. Vernooij, Meike; id_orcid, Frank J. Wolters, Meike W. Vernooij, Yaqub, Amber, Dommershuijsen, Lisanne J., Ikram, Mohammad Kamran, J. Dommershuijsen, Lisanne   +22 more
core   +4 more sources

Plasma Alzheimer's biomarkers and physical functions in aging adults with and without motoric cognitive risk syndrome

Experimental Gerontology
Background: Mobility impairments such as slowed gait and diminished functional capacity are increasingly recognized as early indicators of neurodegenerative processes in aging, including Alzheimer's disease.
Pei-Hao Chen, Sang-I Lin, Ying-Yi Liao, Gwo-Chi Hu, Fang-Yu Cheng   +4 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Purpose in Life and Motoric Cognitive Risk Syndrome

, 2020
Purpose in life – feeling that one’s life is goal-oriented and directed – has been associated consistently with better health outcomes, including better physical function (Kim, Kawachi, Chen, & Kubzansky, 2017), lower risk of cardiovascular disease ...
Antonio Terracciano, Yannick STEPHAN, Martina Luchetti, Angelina Sutin   +3 more
core   +1 more source