Results 1 to 10 of about 124,585 (291)

Multiplex PCR for detection of plasmid-mediated colistin resistance determinants, mcr-1, mcr-2, mcr-3, mcr-4 and mcr-5 for surveillance purposes [PDF]

Eurosurveillance, 2018
International audiencePlasmid-mediated colistin resistance mechanisms have been identified worldwide in the past years. A multiplex polymerase chain reaction (PCR) protocol for detection of all currently known transferable colistin resistance genes (mcr ...
Alba, Patricia, Battisti, Antonio, Borowiak, Maria, Bortolaia, Valeria, Carattoli, Alessandra, de Frutos, Cristina, Escobar,, Franco, Alessia, Granier, Sophie A., Guerra, Beatriz, Hammerl, Jens Andre, Hansen, Inge M., Hendriksen, Rene S., Karlsmose Pedersen, Susanne, Kjeldgaard, Jette S., Leekitcharoenphon, Pimlapas, Malhotra-Kumar, Surbhi, Malorny, Burkhard, Perrin-Guyomard, Agnes, Rebelo, Ana Rita, Villa, Laura   +20 more
core   +8 more sources

Phenotypic and genotypic characterization of colistin-resistant Escherichia Coli with mcr-4, mcr-5, mcr-6, and mcr-9 genes from broiler chicken and farm environment

BMC Microbiology, 2023
Background Colistin is an antibiotic used as a last-resort to treat multidrug-resistant Gram-negative bacterial infections. Colistin had been used for a long time in veterinary medicine for disease control and as a growth promoter in food-producing ...
Mulu Lemlem, Erkihun Aklilu, Maizan Mohamed, Nor Fadhilah Kamaruzzaman, Zunita Zakaria, Azian Harun, Susmita Seenu Devan, Intan Noor Aina Kamaruzaman, Mohd Farhan Hanif Reduan, Muthupandian Saravanan   +9 more
doaj   +3 more sources

Genomic Characterization of Prevalent mcr-1, mcr-4, and mcr-5 Escherichia coli Within Swine Enteric Colibacillosis in Spain [PDF]

Frontiers in Microbiology, 2019
Antimicrobial agents are crucial for the treatment of many bacterial diseases in pigs, however, the massive use of critically important antibiotics such as colistin, fluoroquinolones and 3rd–4th-generation cephalosporins often selects for co-resistance ...
Isidro García-Meniño, Dafne Díaz-Jiménez, Vanesa García, María de Toro, Saskia C. Flament-Simon, Jorge Blanco, Azucena Mora   +6 more
doaj   +4 more sources

Multiplex real-time PCR with high-resolution melting analysis for rapid identification of carbapenem and colistin resistance genes in clinical Enterobacterales isolates [PDF]

Scientific Reports
Conventional susceptibility testing requires 18–48 h and often delays therapy, whereas existing molecular assays are costly and limited. Real-time PCR’s ubiquity in hospitals offers a rapid multiplex screening platform.
Sirirat Luk-In, Kamonrat Phopin, Sasina Bangmuangngam, Tanittha Chatsuwan, Dhammika Leshan Wannigama, Aye Mya Sithu Shein, Ratana Lawung, Tanawut Tantimongcolwat   +7 more
doaj   +2 more sources

Synthesis and characterization of Fe3O4/PEG-400/oxalic acid magnetic nanoparticles as a heterogeneous catalyst for the synthesis of pyrrolin-2-ones derivatives [PDF]

Journal of the Serbian Chemical Society, 2021
In this study, oxalic acid was successfully loaded onto Fe3O4/PEG-400 under ultrasonic irradiation and Fe3O4/PEG/oxalic acid as a new nanomagnetic catalyst was synthesized.
Esmaeilzadeh Seyran, Setamdideh Davood
doaj   +1 more source

Molecular epidemiology of mcr gene group [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2020
Colistin and polymyxin B are the “last reserve” antimicrobials for the treatment of extensively drug-resistant Gram-negative bacterial infections. The rapidly increasing prevalence of polymyxin resistance mediated by the mcr gene localized on plasmid DNA
Shedko E.D., Timoshina O.Yu., Azyzov I.S.   +2 more
doaj   +1 more source

Klebsiella pneumoniae Complex Harboring mcr-1, mcr-7, and mcr-8 Isolates from Slaughtered Pigs in Thailand [PDF]

Microorganisms, 2021
Dissemination of the mobile colistin resistance gene mcr in Enterobacterales among humans, animals, and the environment is a public health issue. We characterized mcr genes in the Klebsiella pneumoniae complex (KpnC) isolated from slaughtered pigs in Thailand. The 280 KpnCs consisted of K.
Nattamol Phetburom, Parichart Boueroy, Peechanika Chopjitt, Rujirat Hatrongjit, Yukihiro Akeda, Shigeyuki Hamada, Suphachai Nuanualsuwan, Anusak Kerdsin   +7 more
openaire   +3 more sources

Characterization of two novel colistin resistance gene mcr-1 variants originated from Moraxella spp.

Frontiers in Microbiology, 2023
This study aimed to characterize two novel mcr-1 variants, mcr-1.35 and mcr-1.36, which originated from Moraxella spp. that were isolated from diseased pigs in China. The Moraxella spp.
Yongliang Che, Yongliang Che, Renjie Wu, Renjie Wu, Hongjie Li, Longbai Wang, Longbai Wang, Xuemin Wu, Xuemin Wu, Qiuyong Chen, Qiuyong Chen, Rujing Chen, Rujing Chen, Lunjiang Zhou, Lunjiang Zhou   +14 more
doaj   +1 more source

Emergence of high-level colistin resistance mediated by multiple determinants, including mcr-1.1, mcr-8.2 and crrB mutations, combined with tigecycline resistance in an ST656 Klebsiella pneumoniae

Frontiers in Cellular and Infection Microbiology, 2023
Colistin and tigecycline are usually regarded as the last resort for multidrug-resistant Klebsiella pneumoniae infection treatment. Emergence of colistin and tigecycline resistance poses a global healthcare challenge and is associated with high mortality
Yanfei Wang, Yanfei Wang, Yanfei Wang, Junxin Zhou, Junxin Zhou, Junxin Zhou, Haiyang Liu, Haiyang Liu, Haiyang Liu, Qian Wang, Qian Wang, Qian Wang, Ping Zhang, Ping Zhang, Ping Zhang, Jingyi Zhu, Jingyi Zhu, Jingyi Zhu, Dongdong Zhao, Dongdong Zhao, Dongdong Zhao, Xueqing Wu, Xueqing Wu, Xueqing Wu, Yunsong Yu, Yunsong Yu, Yunsong Yu, Yan Jiang, Yan Jiang, Yan Jiang   +29 more
doaj   +1 more source

Molecular characterization of extended-spectrum ß-lactamase producers, carbapenemase producers, polymyxin-resistant, and fosfomycin-resistant Enterobacterales among pigs from Egypt

Journal of Global Antimicrobial Resistance, 2022
Objectives: To perform the first prospective surveillance evaluating the occurrence of genes encoding colistin resistance, fosfomycin resistance, carbapenemase, or extended-spectrum ß-lactamases (ESBLs) among Enterobacterial isolates recovered from the ...
Mustafa Sadek, José Manuel Ortiz de la Rosa, Mustafa Ramadan, Patrice Nordmann, Laurent Poirel   +4 more
doaj   +1 more source