Results 11 to 20 of about 53,380 (247)

Phenotypic and genotypic characterization of colistin-resistant Escherichia Coli with mcr-4, mcr-5, mcr-6, and mcr-9 genes from broiler chicken and farm environment

BMC Microbiology, 2023
Background Colistin is an antibiotic used as a last-resort to treat multidrug-resistant Gram-negative bacterial infections. Colistin had been used for a long time in veterinary medicine for disease control and as a growth promoter in food-producing ...
Mulu Lemlem, Erkihun Aklilu, Maizan Mohamed, Nor Fadhilah Kamaruzzaman, Zunita Zakaria, Azian Harun, Susmita Seenu Devan, Intan Noor Aina Kamaruzaman, Mohd Farhan Hanif Reduan, Muthupandian Saravanan   +9 more
doaj   +2 more sources

Molecular detection of colistin resistance genes (mcr-1 to mcr-5) in human vaginal swabs

BMC Research Notes, 2018
Objective Colistin resistance has emerged worldwide and has been threatening the efficacy of one of the last-resort antimicrobials used for treatment of multidrug resistant Gram-negative bacteria. While five colistin resistance genes (mcr-1, mcr-2, mcr-3,
Jilei Zhang, Li Chen, Jiawei Wang, Patrick Butaye, Ke Huang, Haixiang Qiu, Xiaomei Zhang, Weijuan Gong, Chengming Wang   +8 more
doaj   +2 more sources

Characterization of two novel colistin resistance gene mcr-1 variants originated from Moraxella spp. [PDF]

Frontiers in Microbiology, 2023
This study aimed to characterize two novel mcr-1 variants, mcr-1.35 and mcr-1.36, which originated from Moraxella spp. that were isolated from diseased pigs in China. The Moraxella spp.
Yongliang Che, Yongliang Che, Renjie Wu, Renjie Wu, Hongjie Li, Longbai Wang, Longbai Wang, Xuemin Wu, Xuemin Wu, Qiuyong Chen, Qiuyong Chen, Rujing Chen, Rujing Chen, Lunjiang Zhou, Lunjiang Zhou   +14 more
doaj   +2 more sources

Co-occurrence of Variants of mcr-3 and mcr-8 Genes in a Klebsiella pneumoniae Isolate From Laos

Frontiers in Microbiology, 2019
Colistin is considered as a last resort antibiotic. The re-use of this antibiotic highlighted the emergence of colistin resistance mediated by chromosomal and plasmidic resistance mechanisms.
Linda Hadjadj, Linda Hadjadj, Sophie Alexandra Baron, Sophie Alexandra Baron, Sophie Alexandra Baron, Abiola Olumuyiwa Olaitan, Abiola Olumuyiwa Olaitan, Serge Morand, Jean-Marc Rolain, Jean-Marc Rolain, Jean-Marc Rolain   +10 more
doaj   +2 more sources

A Preclinical Multifunctional Capsule Robot with Unified Diagnosis and Targeted Thermal Therapy for Gastrointestinal Diseases. [PDF]

Adv Sci (Weinh)
A proof‐of‐concept multifunctional capsule robot integrates diagnostic imaging, magnetic navigation, wireless power transfer, and targeted thermotherapy for gastrointestinal applications. Magnetically guided positioning and stable wireless power enable localized thermal ablation, achieving controlled heating and high cell mortality in vitro.
Zhang H, Sun Y, Zhang X, Lee CK, Li Z, Li Y, Chen H, Mitcheson PD.   +7 more
europepmc   +2 more sources

Associated resistance of Escherichia coli isolated from humans and animals to polymyxin and beta-lactam antibiotics

Антибиотики и Химиотерапия, 2022
Escherichia coli isolates from various sources from 2018 to 2019 were included in the study. Mcr-1 genes were found in two of 105 animal strains (2%) and seven of 928 human strains (0.8%).
O. S. Sulian, V. A. Ageevets, A. A. Sukhinin, I. V. Ageevets, S. R. Abgaryan, S. A. Makavchik, O. A. Kameneva, K. G. Kosyakova, T. M. Mrugova, D. A. Popov, O. E. Punchenko, S. V. Sidorenko   +11 more
doaj   +1 more source

Plasmid maps of pACYC-Para-MCR-1 and pACYC-NP-MCR-1.

, 2023
The plasmid for expressing MCR-1 or M6 under the regulation of arabinose promoter was shown as (A), and the one for expressing target proteins under the regulation of MCR-1 native promoter was shown as (B).
Chenchen Zhang (324804), Siyuan Feng (5998040), Yaxin Li (312731), Lingxuan Lyu (17628265), Yohei Doi (188766), Wanfei Liang (8610954), Fang Bai (1612534), Lin Wang (11986), Lan-Lan Zhong (9702537), Dianrong Zhou (11816537), Jiachen Li (669381), Hui Zhao (7395), Yong Chen (109188), Nicole Stoesser (220513), Guo-Bao Tian (3365051), Lujie Liang (8610960), Wenjing Wei (525144)   +16 more
core   +1 more source

Epidemiology of mobile colistin resistance (mcr) genes in aquatic environments

Journal of Global Antimicrobial Resistance, 2021
: Colistin is one of the last-line therapies against multidrug-resistant Gram-negative pathogens, especially carbapenemase-producing isolates, making resistance to this compound a major global public-health crisis.
Zineb Cherak, Lotfi Loucif, Abdelhamid Moussi, Jean-Marc Rolain   +3 more
doaj   +1 more source

MCR-1-dependent lipid remodelling compromises the viability of Gram-negative bacteria

, 2022
The global dissemination of the mobilized colistin resistance gene, mcr-1, threatens human health. Recent studies by our group and others have shown that the withdrawal of colistin as a feed additive dramatically reduced the prevalence of mcr-1. Although
Fan Bai (303042), Siyuan Feng (5998040), Yaxin Li (312731), Daixi Lin (11816534), Yohei Doi (188766), Wanfei Liang (8610954), Lan-Lan Zhong (9702537), Dianrong Zhou (11816537), Li-Na Qin (6286202), Jiachen Li (669381), Hui Zhao (7395), Yong Chen (109188), Min Dai (219435), Huihui Du (5044175), Guo-bao Tian (8610972), Lujie Liang (8610960)   +15 more
core   +1 more source

Multiplex PCR for detection of plasmid-mediated colistin resistance determinants, mcr-1, mcr-2, mcr-3, mcr-4 and mcr-5 for surveillance purposes [PDF]

, 2018
Background and aim: Plasmid-mediated colistin resistance mechanisms have been identified worldwide in the past years. A multiplex polymerase chain reaction (PCR) protocol for detection of all currently known transferable colistin resistance genes (mcr-1 ...
Hammerl, Jens Andre, Sophie A Granier, Cristina De Frutos Escobar, Kjeldgaard, Jette,, Ana Rita Rebelo, Carattoli, Alessandra, Borowiak, Maria, Valeria Bortolaia, Maria Borowiak, Hendriksen, Rene S., Patricia Alba, Hendriksen, Rene,, Hansen, Inge,, Malorny, Burkhard, Granier, Sophie, Surbhi Malhotra-Kumar, Antonio Battisti, De Frutos Escobar, Cristina, Franco, Alessia, Inge M Hansen, Rene S Hendriksen, Hammerl, Jens,, Pedersen, Susanne,, Leekitcharoenphon, Pimlapas, Hansen, Inge M., Rebelo, Ana Rita, de Frutos, Cristina, Jette S Kjeldgaard, Alessia Franco, Pedersen, Susanne K., Karlsmose Pedersen, Susanne, Malhotra-Kumar, Surbhi, Kjeldgaard, Jette S., Pimlapas Leekitcharoenphon, Alba, Patricia, Burkhard Malorny, Rebelo, Ana-Rita, Alessandra Carattoli, Granier, Sophie A., Beatriz Guerra, Perrin-Guyomard, Agnes, Battisti, Antonio, Bortolaia, Valeria, Escobar, Susanne K Pedersen, Agnes Perrin-Guyomard, Guerra, Beatriz, Laura Villa, Jens Andre Hammerl, Villa, Laura, Pedersen, Susanne, K., Carattoli A, Hendriksen, Rene, S, Leekitcharoenphon P, Hendriksen RS, Hammerl JA, Malorny B, Borowiak M, Battisti A, Rebelo AR, Guerra B, Escobar and Malhotra-Kumar S, Bortolaia V, Granier SA, Kjeldgaard, Jette, S., Hansen IM, de Frutos C, Perrin-Guyomard A, Alba P, Pedersen SK, Villa L, Hammerl, Jens, Andre, Hansen, Inge, M, Kjeldgaard JS, Franco A   +74 more
core   +3 more sources