Results 11 to 20 of about 124,585 (291)
Journal of Global Antimicrobial Resistance, 2022 : Objectives: The extensive spread of colistin resistance represents an enormous concern to infectious disease treatment, because colistin is one of the few effective antibiotics against multidrug-resistant bacterial infections, including carbapenem ...
Hoa Thi Thanh Hoang +7 more
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mcr-1 Identified in Fecal Escherichia coli and Avian Pathogenic E. coli (APEC) From Brazil
Frontiers in Microbiology, 2021 Colisitin-associated resistance in bacteria of food producing animals has gained significant attention with the mcr gene being linked with resistance. Recently, newer variants of mcr have emerged with more than nine variants currently recognized. Reports
Nicolle Lima Barbieri +5 more
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Frontiers in Veterinary Science, 2022 Non-typhoidal salmonella (TS) remains a significant health burden worldwide. In Vietnam, pork accounts for 70% of the total meat consumed, and contamination with Salmonella is high. High levels of antimicrobial resistance (AMR) have emerged among porcine
Niamh Holohan +12 more
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MCR: modern colistin resistance [PDF]
European Journal of Clinical Microbiology & Infectious Diseases, 2016 Recently, plasmid-mediated and, therefore, transferable bacterial polymyxin resistance was discovered in strains from both humans and animals. Such a trait may widely spread geographically, while simultaneously crossing microbial species barriers. This may ultimately render the "last resort" polymyxin antibiotics therapeutically useless.
Caniaux, I. +4 more
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Антибиотики и Химиотерапия, 2022 Escherichia coli isolates from various sources from 2018 to 2019 were included in the study. Mcr-1 genes were found in two of 105 animal strains (2%) and seven of 928 human strains (0.8%).
O. S. Sulian +11 more
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Atorvastatin (Lipitor) by MCR [PDF]
ACS Medicinal Chemistry Letters, 2019 A concise and convergent synthesis of the atorvastatin, the best-selling cardiovascular drug of all time, is presented. Our approach is based on an Ugi reaction, which shortens the current synthetic route and is advantageous over the published syntheses.
Tryfon Zarganes-Tzitzikas +2 more
openaire +3 more sources
Epidemiology of mobile colistin resistance (mcr) genes in aquatic environments
Journal of Global Antimicrobial Resistance, 2021 : Colistin is one of the last-line therapies against multidrug-resistant Gram-negative pathogens, especially carbapenemase-producing isolates, making resistance to this compound a major global public-health crisis.
Zineb Cherak +3 more
doaj +1 more source
Antibiotics, 2021 Background: In order to estimate the prevalence of plasmid borne colistin resistance and to characterize in detail the mcr-positive isolates, we carried out a sentinel testing survey on the intestinal carriage of plasmid-mediated colistin-resistant ...
Jan Tkadlec +8 more
doaj +1 more source
Molecular detection of colistin resistance genes (mcr-1 to mcr-5) in human vaginal swabs
BMC Research Notes, 2018 Objective Colistin resistance has emerged worldwide and has been threatening the efficacy of one of the last-resort antimicrobials used for treatment of multidrug resistant Gram-negative bacteria. While five colistin resistance genes (mcr-1, mcr-2, mcr-3,
Jilei Zhang +8 more
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Insights into the Ecological Roles and Evolution of Methyl-Coenzyme M Reductase-Containing Hot Spring Archaea [PDF]
, 2019 Several recent studies have shown the presence of genes for the key enzyme associated with archaeal methane/alkane metabolism, methyl-coenzyme M reductase (Mcr), in metagenome-assembled genomes (MAGs) divergent to existing archaeal lineages.
Chen, Ya-Ting +17 more
core +3 more sources